Poor Oral Health-Related Quality of Life in Pre- and Post-Liver Transplantation Patients

Santos-Lins, Larissa Souza; Aguiar, Inácio; Codes, Liana; Evangelista, M. A.; Castro, Alessandra De; Bittencourt, Paulo Lisboa; Cavalcanti, A.; Paraná, Raymundo; Lins-Kusterer, Liliane

doi:10.2174/1874210602115010196

Cited by 2 publications

(2 citation statements)

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“…Convergent validity between RAND-36 domains and Work Ability Index (WAI) was conducted. The WAI scale measures the self-perceived physical and mental health, and have been previously used in individuals with chronic liver disease, presenting good reliability (9,22) . The WAI total score ranges from 7 to 49, and high scores indicate good work ability (23) .…”

Section: Convergent Validitymentioning

confidence: 99%

“…HRQoL is frequently used as an outcome measure that evaluates the quality of care, while the Short Form-36 (SF-36) is a reliable tool that provide good reliability and validity for assessing the individuals' quality of life in different stages of an illness (3)(4)(5)(6)(7)(8)(9)(10)(11) . In August 2021, a search in PubMed (https://www.ncbi.nlm.nih.gov) database using the term "SF 36" retrieved 92,145 articles.…”

Section: Introductionmentioning

confidence: 99%

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Validation of the RAND 36-Item Health Survey questionnaire in Brazil

Lins-Kusterer

Aguiar

Santos-Lins

et al. 2022

Arq. Gastroenterol.

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Background: Health-related quality of life is frequently used as an outcome measure that improves the quality of care. The SF-36 and RAND-36 were derived from the Medical Outcomes Study. Objective The present study aimed to validate the RAND-36 in Brazil, in healthy individuals and patients with liver disease. Methods: Confirmatory factor analysis (CFA) was conducted by using JASP Software. The parameters of the items were estimated using the Robust Diagonally Weighted Least Squares (RDWLS) approach. Comparative fit index (CFI), Goodness-of-fit index (GFI), Tucker-Lewis Index (TLI) and the root mean square error of approximation (RMSEA) were evaluated. Internal consistency was measured using the Composite reliability index. Convergent validity between RAND-36 domains and Work Ability Index (WAI) was conducted. Results: This validation study included 763 individuals, 400 (52.4%) with chronic liver disease. The most prevalent liver diseases were hepatitis C (13.9%), alcoholic liver disease (11.8%), and steatosis (12.1%). The measurement model tested using the CFA obtained the following adjustment indicators: X2 (df): 599.65 (498); CFI: 0.998; GFI: 0.998; TLI: 0.998; RMSEA: 0.016 (90%CI: 0.011-.021). Convergent validity of RAND-36 and total WAI ranged from medium to large correlation. Conclusion: The RAND-36 is effective in measuring the perception of health-related quality of life in individuals with and without chronic liver disease. The results of our study support the developer’s claims for the reliability of the RAND-36 version 1 as a measure of health-related quality of life. The evidence for the construct validity of the RAND-36 was substantial.

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Section: Convergent Validitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Validation of the RAND 36-Item Health Survey questionnaire in Brazil

Lins-Kusterer

Aguiar

Santos-Lins

et al. 2022

Arq. Gastroenterol.

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Poor Oral Health-Related Quality of Life and Frailty Among PLWHIV: A Cross-Sectional Study

Santos-Lins,

Santos,

Amaral

et al. 2024

J Int Soc Prev Community Dent

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Aims: This study aimed to explore the association between frailty and pre-frailty in people living with human immunodeficiency virus (PLWHIV), focusing on their oral health-related quality of life (OHRQoL) and health-related quality of life (HRQoL). Materials and Methods: A cross-sectional study was conducted with 184 PLWHIV. Frailty status was assessed using Fried’s frailty criteria, categorizing participants as robust, pre-frail, or frail. The oral health profile was evaluated using the World Health Organization and European Association of Public Dental Health criteria. OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14), while HRQoL was measured using the 36-Item Short-Form Health Survey version 2 (SF-36v2). Descriptive statistics were calculated, and associations were analyzed using Spearman’s correlation and one-way ANOVA, with significance set at P ≤ 0.05. Results: The pre-frail and frail PLWHIV groups reported significantly lower HRQoL scores across all domains compared to the robust group. Additionally, robust PLWHIV exhibited better oral health outcomes, with higher mean OHIP-14 scores (P = 0.005), attributed to fewer missing teeth (P = 0.019) and a higher number of filled teeth (P = 0.031). The total OHIP-14 score showed a moderate negative correlation with various SF-36v2 domains, particularly in the pre-frail and frail groups. Specifically, physical pain and physical disability subdomains of HRQoL were most affected by poorer OHRQoL. Conclusions: Frail and pre-frail PLWHIV demonstrated significantly poorer OHRQoL compared to robust PLWHIV, with a particular impact on physical pain and physical disability. A negative correlation between OHRQoL and HRQoL was evident, especially in the frail and pre-frail groups, highlighting the interrelationship between oral health and overall well-being in this population. Clinically, this suggests that improving OHRQoL could be an essential component of healthcare for frail and pre-frail PLWHIV, as enhancing oral health may positively influence their general health outcomes. Targeted interventions to manage frailty and improve oral health are needed to enhance both OHRQoL and HRQoL in this vulnerable group.

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Poor Oral Health-Related Quality of Life in Pre- and Post-Liver Transplantation Patients

Cited by 2 publications

References 38 publications

Validation of the RAND 36-Item Health Survey questionnaire in Brazil

Validation of the RAND 36-Item Health Survey questionnaire in Brazil

Poor Oral Health-Related Quality of Life and Frailty Among PLWHIV: A Cross-Sectional Study

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