2011
DOI: 10.1155/2011/436752
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Poorly Differentiated Uterine or Cervical Sarcoma in a Young Dog

Abstract: A 1.5 year old, female, spayed, Labrador retriever with a history of three abdominal surgeries within the previous two months presented to the North Carolina State University Veterinary Teaching Hospital for evaluation of a pelvic inlet mass causing fecal tenesmus, obstipation, and dysuria. Abdominal ultrasound revealed a caudal abdominal mass extending into the pelvic cavity. Cytologic evaluation of the mass showed a pleomorphic round to fusiform cell population with histiocytic and suppurative inflammation. … Show more

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Cited by 1 publication
(2 citation statements)
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“…Immunohistochemical studies often do not include myogenin or MyoD1 but are negative for desmin. 33 Young age, or genitourinary location, should indicate a possible RMS despite negative desmin staining. Increased availability of myogenin, MyoD1, or other primitive myogenic markers may help diagnose alveolar and embryonal RMS in these circumstances.…”
Section: Frequency Of Published Casesmentioning
confidence: 99%
See 1 more Smart Citation
“…Immunohistochemical studies often do not include myogenin or MyoD1 but are negative for desmin. 33 Young age, or genitourinary location, should indicate a possible RMS despite negative desmin staining. Increased availability of myogenin, MyoD1, or other primitive myogenic markers may help diagnose alveolar and embryonal RMS in these circumstances.…”
Section: Frequency Of Published Casesmentioning
confidence: 99%
“…These neoplasms may be misdiagnosed as "undifferentiated sarcoma," "anaplastic sarcoma," or even a "poorly differentiated sarcoma" depending on the phenotype of the variant. 33,48,146,158 Diagnostic features of skeletal muscle differentiation may not be evident at the light microscopic level and may only be recognized by immunohistochemistry or electron microscopy. This article reviews the diagnostic features, pathogenesis, and classification of rhabdomyosarcomas in dogs and compares them with their human counterparts to facilitate the recognition of these tumors by veterinary diagnostic pathologists.…”
mentioning
confidence: 99%