This study investigates muscle proteins in Russian (Acipenser gueldensiaedtii Brandt), Siberian (Acipenser baerii Brandt), and Amur (Acipenser schrenckii Brandt) sturgeons using the method of polyacryl amide gel electrophoresis. A group of fractions, which is presumably the product of a polyallelic duplicated MY 1* locus, is recorded among the general pool of proteins. Data from densitometric analysis makes it pos sible to put forward a hypothesis about an eight gene determination of this system of proteins. The highest heterogeneity and polymorphism was revealed in the Russian sturgeon. Analysis of the genotype distribution in samples of the studied species allowed us to make an assumption that the genetic structure of spawning sturgeon stocks is significantly metamorphosed under the influence of anthropogenic and natural factors.