Population‐based epidemiologic study of Wilson’s disease in Taiwan

Lai, Chao-Hung; Tseng, Hung Fu

doi:10.1111/j.1468-1331.2009.02946.x

Cited by 22 publications

(26 citation statements)

References 23 publications

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“…Other limitations of the NHIRD have been discussed in our previous NHIRD studies [10][11][12][13][14] . However, for the present study, the limitations have only a trivial effect, because ICD-9 code 321.0 is very specific and the discharge diagnosis of cryptococcal meningitis is usually straightforward.…”

Section: Discussionmentioning

confidence: 99%

Nationwide Population-Based Epidemiologic Study of Cryptococcal Meningitis in Taiwan

Chen

Lai²

2011

Neuroepidemiology

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Background: Little is known about the epidemiology of cryptococcal meningitis in Taiwan. The aim of this study was to conduct the first nationwide population-based epidemiologic study of cryptococcal meningitis in Taiwan. Methods: Cases of cryptococcal meningitis were identified from the annual hospitalization discharge claims of the National Health Insurance Research Database with the corresponding ICD-9 code 321.0 from January 2000 to December 2007. Results: A total of 845 incident cases of cryptococcal meningitis were detected. Among them, 109 patients (12.9%) had human immunodeficiency virus (HIV) infection. The average incidence was 4.7 per million person-years. The incidence remarkably increased in the age group of 60–69 years, peaked in the age group of 70–79 years, and fell after the age of 80 years. The average incidence for men was 2.2-fold higher than that for women. The most common complication was obstructive hydrocephalus in 15.3% of the patients, followed by acute respiratory failure in 12.0% of the patients. Conclusion: This is the first population-based epidemiologic study of cryptococcal meningitis in Taiwan. The incidence was stable during the study period, and most cases were non-HIV related.

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Section: Discussionmentioning

confidence: 99%

Nationwide Population-Based Epidemiologic Study of Cryptococcal Meningitis in Taiwan

Chen

Lai²

2011

Neuroepidemiology

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“…Rheumatoid arthritis is a common and destructive chronic systemic inflammatory disease with the average age-adjusted annual incidence rate 15.8 per 100 000 in Taiwan. 1,2 A systematic review and meta-analysis has shown that there is an increased incidence of cardiovascular events in patients with RA, such as acute myocardial infarction, stroke, and cardiac death. 3 Most studies investigating mortality in patients with RA compared to those without RA have found increased mortality rates largely due to cardiovascular diseases (CVD), specifically coronary artery diseases (CAD).…”

Section: Introductionmentioning

confidence: 99%

Hydroxychloroquine may be associated with reduced risk of coronary artery diseases in patients with rheumatoid arthritis: A nationwide population-based cohort study

et al. 2018

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“…We have previously established the population-based epidemiological data of motor neuron diseases [9] , Creutzfeldt-Jakob disease, multiple sclerosis [10] and Wilson's disease [11] from the National Health Insurance Research Database (NHIRD). At least 215 studies utilizing the same database have been published.…”

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confidence: 99%

Nationwide Population-Based Epidemiological Study of Myasthenia Gravis in Taiwan

Lai¹,

Tseng²

2010

Neuroepidemiology

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Background: The purpose of this study is to investigate the epidemiology and medical expenses of myasthenia gravis (MG) in Taiwan. Methods: Cases of MG were identified from the National Health Insurance Research Database with corresponding codes of the International Classification of Diseases, ninth revision (ICD-9), from January 2000 to December 2007. Age- and sex-specific incidences were estimated by dividing the incidence number by population data obtained from the Department of Statistics, Ministry of the Interior. Results: During the study period, 5,211 cases were identified. The incidence ratio of males to females was 0.68. The average annual incidence rate was 2.1/100,000. MG occurred in all age groups with a higher incidence in older individuals and the lowest incidence in the 10- to 14-year-olds for both sexes. Among the 5,211 cases, 615 (12%) had a neoplasm of the thymus. The prevalence increased steadily during the study period from 8.4/100,000 in 2000 to 14.0/ 100,000 in 2007. Conclusions: This is the first population-based epidemiological study of MG in Taiwan. The incidence rate and prevalence were higher than in most published studies, especially in old age groups.

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Population‐based epidemiologic study of Wilson’s disease in Taiwan

Abstract: This is the first population-based epidemiologic study of Wilson's disease in Taiwan. Because of the effective and affordable treatment, the prevalence of Wilson's disease in Taiwan is expected to increase continuously.

Cited by 22 publications

References 23 publications

Nationwide Population-Based Epidemiologic Study of Cryptococcal Meningitis in Taiwan

Nationwide Population-Based Epidemiologic Study of Cryptococcal Meningitis in Taiwan

Hydroxychloroquine may be associated with reduced risk of coronary artery diseases in patients with rheumatoid arthritis: A nationwide population-based cohort study

Nationwide Population-Based Epidemiological Study of Myasthenia Gravis in Taiwan

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