Population‐Based Incidence of Intussusception and a Case‐Control Study to Examine the Association of Intussusception with Natural Rotavirus Infection among Indian Children

Bahl, Rajiv; Saxena, Manju; Bhandari, Nita; Taneja, Sunita; Mathur, Meera; Parashar, Umesh D.; Gentsch, Jon R.; Shieh, Wun‐Ju; Zaki, Sherif R.; Glass, Roger I.; Bhan, Maharaj Kishan

doi:10.1086/605045

Cited by 43 publications

(30 citation statements)

References 36 publications

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“…This is similar to the findings in other studies [21] [26] [27]. However, a similar study among Taiwanese children reported peak age in children 1 to 3 years [28].…”

Section: Discussionsupporting

confidence: 92%

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Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria

Tagbo¹,

Mwenda²,

Eke³

et al. 2014

WJV

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124(15.6%) and abnormal/absent bowel sound 43 (15.9%). Diagnosis was essentially with the aid of abdominal ultrasonography, 38 (63.3%) while surgery (laparotomy) was the treatment of choice in most cases 48 (80.0%). The case fatality rate was 3 (5.0%). Conclusion: None of the cases studied could be directly linked to rotavirus vaccinations. But seasonal peak incidence coincided with rotavirus diarrhea peak incidence. Efforts should be made to institute post-rotavirus vaccine licensure prospective surveillance study in order to fully determine any relationship between rotavirus vaccination and intussusception in Enugu, South east, Nigeria.

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“…This is similar to the findings in other studies [21] [26] [27]. However, a similar study among Taiwanese children reported peak age in children 1 to 3 years [28].…”

Section: Discussionsupporting

confidence: 92%

“…Data on pre-vaccine intussusception rates in developing countries especially in the sub-Saharan Africa are required to facilitate informed decision making about use of new rotavirus vaccines [21].…”

Section: Introductionmentioning

confidence: 99%

Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria

Tagbo¹,

Mwenda²,

Eke³

et al. 2014

WJV

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“…Intussusception occurs in approximately 17.7 children per 100,000 per year in the india. 8 Population-based incidence of intussusception and a case-control study to examine the association of intussusception with natural rotavirus infection among indian children. 9 Of these, 60% of cases occur before 1 year of age and 80% before 2 years.…”

Section: Resultsmentioning

confidence: 99%

“…8 Population-based incidence of intussusception and a case-control study to examine the association of intussusception with natural rotavirus infection among indian children. 9 Of these, 60% of cases occur before 1 year of age and 80% before 2 years. Its incidence is highest between 5 and 9 months of age, being uncommon in neonates.…”

Section: Resultsmentioning

confidence: 99%

Current Trends in Paediatric Intususceptions

M¹,

Basawaraj²,

Tulsi³

et al. 2015

jemds

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Intussusception is the major cause of acute intestinal obstruction in infants. The classic clinical triad of intussusception is colicky abdominal pain, vomiting and bloody stools. However, only 20% of patients present with this triad. OBJECTIVES: The objective of this article with a series of cases of intussusception is to review the spectrum of clinical presentation of this disease entity and also to study the effectiveness of non-surgical intervention in children with intussusception using barium enema reduction under fluoroscopy. METHODS AND RESULTS: This prospective study spread over a period of 3 year and six months from October 2010 to march 2014 was carried out in tertiary care hospital in south Bangalore. Complete review of medical records for clinical and demographic information was only performed for those cases fulfilling diagnostic certainty (Definite intussusception). During the surveillance period, A total of 40 patients, diagnosed cases were included in this study. The majority (78.4%) of the cases occurred in the first year of life. The male: female ratio was 2.4: 1. Intussusception cases occurred round the year with no distinct seasonality. No intussusception-associated death was recorded. Cases identified in the study were similar in presentation and demographics as those observed in other south East Asian settings. Clinical presentation of the patients were pain abdomen, vomiting, blood in stools, fever and loose stools. Among the patients who were admitted the time between the onset of symptoms and hospitalization was between 36 to 48 hours, After stabilizing them haemodynamically they were subjected to definitive procedure, Barium enema reduction was tried in all patients, exclusion criteria was patients with clinical and radiological sign and symptoms of peritonitis, duration of symptoms more than 30hours and massive abdominal distension. Out of forty cases, thirty seven (81.8%) were reduced by fluoroscopic guided barium enema, those who failed among them, one (2.5) was reduced by pneumatic reduction, one (2.5) was reduced by ultrasound guided pneumatic reduction and only one (2.5%) patient required surgical interventions, reduced manually during surgery. No mortalities were recorded during the study. There was one recurrence noted in our study 15 days after discharge and was subsequently treated with fluoroscopic guided contrast reduction. CONCLUSION: Surgical intervention in intussusception can be prevented by non-operative reduction especially if presented early and no signs of peritonitis.

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“…A live rotavirus vaccine has been withdrawn due to claims of increased cases of intussuception after its administration [14]. But recent reports and a population based study of intussuception incidence conducted in Delhi has denied any association between natural rotavirus infection and intussuception [15].…”

Section: Discussionmentioning

confidence: 99%

Paediatric Surgical Pathology – a Profile of Cases from Western India and Review of Literature

Shah

Kamdar³

et al. 2015

JCDR

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Aim: The paediatric surgical pathology specimens manifest a wide spectrum of morphological and histological features. The present work has been undertaken to know the prevalence and to describe the profile of paediatric surgical pathology specimens from western India as seen in Ahmedabad, India from 2008 to 2010. Materials and Methods:We reviewed 140 paediatric surgical specimens, 118 specimens rendered definitive diagnosis were included for the analysis. Cases were divided in two groups, one of developmental and congenital conditions and another of acquired lesions.Results: This study included 118 patients of which 79.3 % were male and 20.7 % were female. Age range of the patients was one day to twelve years. Children of one month to one year age group (infants) were the most vulnerable (31.3% cases). Group of developmental and congenital conditions consisted

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Population‐Based Incidence of Intussusception and a Case‐Control Study to Examine the Association of Intussusception with Natural Rotavirus Infection among Indian Children

Abstract: The incidence of intussusception among Indian infants appears to be lower than that reported in other middle- and high-income countries. Natural rotavirus infection does not appear to be a major cause of intussusception in Indian infants.

Cited by 43 publications

References 36 publications

Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria

Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria

Current Trends in Paediatric Intususceptions

Paediatric Surgical Pathology – a Profile of Cases from Western India and Review of Literature

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