Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study

Abstract

According to the data, a large proportion (10%) of the Spanish population has some evidence of thyroid dysfunction. High TPOAb concentrations were associated with both hypo- and hyperthyroidism, whereas high UI concentrations were associated with hypothyroidism.

Prevalence of thyroid dysfunction in a Large Southern European Population. Analysis of modulatory factors. The APNA study

“…Our results diverge somewhat from some data already reported in our country. A recent study carried out on 4554 individuals reported a prevalence of treated, untreated subclinical and untreated clinical hypothyroidism of 4.2%, 4.6% and 0.3%, respectively . However, the prevalence of total hyperthyroidism in the study in question was 0.8%, a value notably lower than that which we found in Navarra.…”

Prevalence of Undiagnosed Hypothyroidism in Europe: A Systematic Review and Meta-Analysis

“…The sample size of selected studies varied between 307 [34] and 80,490 [35]. The studies included sample populations from Austria [35], Belgium [36], Bulgaria [37], Denmark [38], Germany [39, 40], Italy [16, 18, 41], Norway [15, 42], Spain [17, 19, 34, 43], The Netherlands [44, 45], the UK [46, 47], and Turkey [48]. …”

“…The prevalence of undiagnosed total (subclinical plus overt) hypothyroidism was ascertained in 11 studies [15-19, 40-43, 46, 48], with estimates ranging between 2.7% [41] and 12.8% [16]. The prevalence of hypothyroidism was lower in men than in women for subclinical (men: min.…”

“…The estimates can vary between 0.1 and 12.5%, depending on the definition used [15, 16]. For example, some studies evaluated the prevalence of undiagnosed and untreated subclinical and/or overt hypothyroidism [17-19], while others addressed previously diagnosed and treated hypothyroidism [20, 21]. Patients with undiagnosed hypothyroidism are not treated for the disease and therefore might be at higher risk of developing long-term complications, such as serious and even fatal cardiovascular diseases, diabetes, or others [22-25].…”

Temporal trends in thyroid‐stimulating hormone (TSH) and thyroid peroxidase antibody (ATPO) testing across two phases of iodine fortification in Tasmania (1995‐2013)

“…Disordered thyroid function is commonly diagnosed in the general population, its prevalence and disease spectrum influenced by age, gender and prevailing levels of iodine nutrition. Studies have reported the prevalence of hypothyroidism at 4.6%‐10% and that of hyperthyroidism at 0.5%‐2.2% in the adult population . In the Australian context, an estimated 0.5% and 5% of adults have overt and subclinical hypothyroidism, respectively, whilst overt and subclinical hyperthyroidism are each reported to affect approximately 0.3% of the population .…”