Population-based patterns of treatment and survival for patients with stage I and II non-small cell lung cancer aged 65–74 years and 75 years or older

Driessen, Elisabeth J.M.; Detillon, Deniece D.E.M.A.; Bootsma, G.; Ruysscher, Dirk De; Veen, Eelco J.; Aarts, Mieke J.; Janssen‐Heijnen, M.L.G.

doi:10.1016/j.jgo.2019.03.001

Cited by 16 publications

(19 citation statements)

References 39 publications

(64 reference statements)

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Section: Resultsmentioning

confidence: 99%

“…Of the twenty studies that examined lung cancer, eight studies focused on non-small cell lung cancer (NSCLC) 18,44–50 , three on small-cell lung cancer (SCLC) 19,51,52 , and nine on all lung cancer cases 37–43,49,53,54 (Table 3) . Six studies aimed to evaluate age disparities in surviva1 41,43,45,48–50 . Seven studies analysed data from the Netherlands 18,19,43,48–51 , six from the U.S.A 37,44,47,52,54 , and the remaining studies presented data from Finland 53 , Taiwan 38,46 , Korea 39 , the Czech Republic 41 , England 40 , and Germany 42 .…”

Section: Resultsmentioning

confidence: 99%

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Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Pilleron

Gower

Janssen‐Heijnen

et al. 2020

Preprint

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Objective: To identify patterns of age disparities in cancer survival, using colon and lung cancer as exemplars. Methods: We conducted a systematic review of literature published in EMBASE, MEDLINE, Scopus, and Web of Science according to PRISMA guidelines. We included population-based studies in patients with colon or lung cancer. We assessed the quality of included studies against selected evaluation domains from the QUIPS Tool, and items concerning statistical reporting. We evaluated age disparities using the absolute difference in survival or mortality rates between middle-aged group and the oldest age group, or by describing survival curves. Results: Out of 2,162 references reviewed, we retained 35 studies (15 for colon, 18 for lung, 2 for both sites). Regardless of the cancer site, included studies were highly heterogeneous and often of poor quality. The magnitude of age disparities in survival varied greatly by sex, ethnicity, socio-economic status, stage at diagnosis, cancer site and morphology, the number of nodes examined, and by treatment strategy. Although results were inconsistent for most characteristics, we consistently observed greater age disparities for females with lung cancer compared to males. Also, age disparities increased with more advanced stages for colon cancer and decreased with more advanced stages for lung cancer. Conclusions: Although age is one of the most important prognostic factors in cancer survival, age disparities in colon and lung cancer survival have so far been understudied in population-based research. Further studies are needed to better understand age disparities in colon and lung cancer survival. (PROSPERO registration number: CRD42020151402).

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Pilleron

Gower

Janssen‐Heijnen

et al. 2020

Preprint

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“…62 75 While most studies included all stages at diagnosis, some studies restricted their sample to specific stage(s): stage I cancer, 50 65-68 stages I-IIIa, 51 stages IIIb and IV, 52 stage III 54 and stages I or II. 55 Fifteen studies included patients of all ages at diagnosis, 19 44 69 76 or 65. 52 54 55 The studies used age categories that differed widely in terms of number and boundaries.…”

Section: Open Accessmentioning

confidence: 99%

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

et al. 2021

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ObjectivesTo identify patterns of age disparities in cancer survival, using colon and lung cancer as exemplars.DesignSystematic review of the literature.Data sourcesWe searched Embase, MEDLINE, Scopus and Web of Science through 18 December 2020.Eligibility criteriaWe retained all original articles published in English including patients with colon or lung cancer. Eligible studies were required to be population-based, report survival across several age groups (of which at least one was over the age of 65) and at least one other characteristic (eg, sex, treatment).Data extraction and synthesisTwo independent reviewers extracted data and assessed the quality of included studies against selected evaluation domains from the QUIPS tool, and items concerning statistical reporting. We evaluated age disparities using the absolute difference in survival or mortality rates between the middle-aged group and the oldest age group, or by describing survival curves.ResultsOut of 3047 references, we retained 59 studies (20 for colon, 34 for lung and 5 for both sites). Regardless of the cancer site, the included studies were highly heterogeneous and often of poor quality. The magnitude of age disparities in survival varied greatly by sex, ethnicity, socioeconomic status, stage at diagnosis, cancer site, and morphology, the number of nodes examined and treatment strategy. Although results were inconsistent for most characteristics, we consistently observed greater age disparities for women with lung cancer compared with men. Also, age disparities increased with more advanced stages for colon cancer and decreased with more advanced stages for lung cancer.ConclusionsAlthough age is one of the most important prognostic factors in cancer survival, age disparities in colon and lung cancer survival have so far been understudied in population-based research. Further studies are needed to better understand age disparities in colon and lung cancer survival.PROSPERO registration numberCRD42020151402.

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“…intervention and comparison: SBRT versus CRT (including conventional radiotherapy, [ 15 , 16 , 19 , 21 , 26 ] conventional fractionated radiotherapy, [ 17 , 20 , 23 , 25 , 27 ] 3D conformal radiotherapy, [ 9 , 11 , 13 , 14 , 18 ] and accelerated hypofractionated radiotherapy [ 13 ] );…”

Section: Methodsmentioning

confidence: 99%

A meta-analysis comparing stereotactic body radiotherapy vs conventional radiotherapy in inoperable stage I non-small cell lung cancer

Wang

et al. 2020

Medicine

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Population-based patterns of treatment and survival for patients with stage I and II non-small cell lung cancer aged 65–74 years and 75 years or older

Cited by 16 publications

References 39 publications

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

A meta-analysis comparing stereotactic body radiotherapy vs conventional radiotherapy in inoperable stage I non-small cell lung cancer

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Population-based patterns of treatment and survival for patients with stage I and II non-small cell lung cancer aged 65–74 years and 75 years or older

Cited by 16 publications

References 39 publications

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

A meta-analysis comparing stereotactic body radiotherapy vs conventional radiotherapy in inoperable stage I non-small cell lung cancer

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Product

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Population-based patterns of treatment and survival for patients with stage I and II non-small cell lung cancer aged 65–74 years and 75 years or older