Population-Based Reference Values for 3D Echocardiographic LV Volumes and Ejection Fraction

Chahal, Navtej; Lim, Tiong Keng; Jain, Piyush; Chambers, John C.; Kooner, Jaspal S.; Senior, Roxy

doi:10.1016/j.jcmg.2012.07.014

Cited by 86 publications

(83 citation statements)

References 13 publications

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“…The longitudinal decrease in LV EDV and stroke volume we observed in participants who underwent follow-up is consistent with cross-sectional age relationships reported in the MESA cohort at baseline (13). More recent cross-sectional studies in healthy volunteers with three-dimensional echocardiography have shown an inverse relationship between LV volume and age (25)(26)(27). These volume relationships are in contrast to the findings of earlier studies that reported LV volume increased with age (28,29).…”

Section: Cardiac Imaging: Adverse Left Ventricular Remodelingsupporting

confidence: 86%

Adverse Left Ventricular Remodeling and Age Assessed with Cardiac MR Imaging: The Multi-Ethnic Study of Atherosclerosis

Eng

McClelland²,

Gomes

et al. 2016

Radiology

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).q RSNA, 2015 Purpose:To evaluate age-related left ventricular (LV) remodeling during longitudinal observation of a large cohort of asymptomatic individuals who were free of clinical cardiovascular disease at baseline. Materials and Methods:The applicable institutional review boards approved this study, and all participants gave informed consent. Cardiac magnetic resonance (MR) imaging was used to identify longitudinal changes in LV structure and function in 2935 participants who underwent baseline and follow-up cardiac MR imaging in the Multi-Ethnic Study of Atherosclerosis. Participants were free of clinical cardiovascular disease at baseline. Participants who experienced an incident coronary heart disease event were excluded. Data were analyzed with multivariable mixed-effects regression models in which the outcome was cardiac MR imaging measurement, and the covariates included follow-up time and cardiac risk factors. Results:Participants were aged 54-94 years at follow-up, and 53% of the participants were women. Median time between baseline and follow-up cardiac MR imaging was 9.4 years. Over this period, LV mass increased in men and decreased slightly in women (8.0 and 21.6 g per decade, respectively; P , .001). In both men and women, LV enddiastolic volume decreased (29.8 and 213.3 mL per decade, respectively; P , .001), stroke volume decreased (28.8 and 28.6 mL per decade, respectively; P , .001), and mass-to-volume ratio increased (0.14 and 0.11 g/mL per decade, respectively; P , .001). Change in LV mass was positively associated with systolic blood pressure and body mass index and negatively associated with treated hypertension and high-density lipoprotein cholesterol level. In men, the longitudinal LV mass increase was in contrast to a cross-sectional pattern of LV mass decrease. Conclusion:As patients age, the LV responds differently in its mass and volume between men and women, although both men and women experience increased concentric LV remodeling with age. In men, the opposition of longitudinal and cross-sectional changes in LV mass highlights the importance of longitudinal study.q RSNA, 2015

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Section: Cardiac Imaging: Adverse Left Ventricular Remodelingsupporting

confidence: 86%

Adverse Left Ventricular Remodeling and Age Assessed with Cardiac MR Imaging: The Multi-Ethnic Study of Atherosclerosis

Eng

McClelland²,

Gomes

et al. 2016

Radiology

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“…Pregnant or lactating women, athletes, and subjects addicted to alcohol were also excluded by a few authors (15,16,60), and some studies also evaluated smoking (15,21,38,82), anaemia and fever (15,16) as exclusion criteria. However, in some studies (15,19,38,43,52,54,63,82), inclusion criteria were well defined, in other sufficiently explained (20,21,24,30,50,52,61,67,70,74,76), while in few works the criteria were more generic (23,24,26,58,59,69,73).…”

Section: Inclusion and Exclusion Criteriamentioning

confidence: 99%

“…In particular, four major multi-center studies (the Normal Reference Range for Echocardiography-NORRE-European, The Japanese Normal Values for Echocardiographic Measurement Project-JAMP, The Echocardiographic Measurements in Normal Chinese Adults-Eminca, and The Normal Echocardiographic Measurements in a Korean population-NORMAL-trials) are currently ongoing and normative data for many 2D and a few 3D parameters have been published (15)(16)(17)(18)(19)(20)(21)(22)(23)52). Contemporary, different centers addressed the need of having normative data for new parameters coming from 3D echocardiography (45)(46)(47)(48)(49)(50)(51)(52)(53)(54)(55)(56)(57)(58) and deformation analysis . At present there is a big amount of echocardiographic normative data , but these data remain fragmentary and at times , difficult to find and time consuming .…”

Section: Introductionmentioning

confidence: 99%

Adult echocardiographic nomograms: overview, critical review and creation of a software for automatic, fast and easy calculation of normal values

Cantinotti¹,

Giordano²,

Paterni³

et al. 2017

J. Thorac. Dis.

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There is a crescent interest on normal adult echocardiographic values and the introduction of new deformation imaging and 3D parameters pose the issue of normative data. A multitude of nomograms has been recently published, however data are often fragmentary, difficult to find, and their strengths/ limitations have been never evaluated. Aims: (I) to provide a review of current echocardiographic nomograms; (II) to generate a tool for easy and fast access to these data. A literature search was conducted accessing the National Library of Medicine using the keywords: 2D/3D echocardiography, strain, left/ right ventricle, atrial, mitral/tricuspid valve, aorta, reference values/nomograms/normal values. Adding the following keywords, the results were further refined: range/intervals, myocardial velocity, strain rate and speckle tracking. Forty one published studies were included. Our study reveals that for several of 2D/3D parameters sufficient normative data exist, however, a few limitations still persist. For some basic parameters (i.e., mitral/tricuspid/pulmonary valves, great vessels) and for 3D valves data are scarce. There is a lack of studies evaluating ethnic differences. Data have been generally expressed as mean values normalised for gender and age instead of computing models incorporating different variables (age/gender/body sizes) to calculate z scores. To summarize results a software (Echocardio-Normal Values) who automatically calculate range of normality for a broad range of echocardiographic measurements according to age/gender/weight/ height, has been generated. We provide an up-to-date and critical review of strengths/limitation of current adult echocardiographic nomograms. Furthermore we generated a software for automatic, easy and fast access to multiple echocardiographic normative data.

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“…Sus resultados mostraron que el ETT 2D infraestima los volúmenes del VI, pero sin diferir en FEVI. De igual manera se evidenció la influencia de la etnia en los rangos de normalidad (Chahal et al 2012). …”

Section: Aplicacionesunclassified

Ecocardiografía avanzada: aplicación clínica actual del análisis de deformación miocárdica y de la imagen tridimensional

Recalde

2017

REMCB

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Artículo de revisión MECÁNICA CARDÍACA: ANÁLISIS DE DE-FORMACIÓN MIOCÁRDICAEn los últimos años se ha puesto de manifiesto la necesidad de trasladar el momento del diagnóstico de las enfermedades cardiovasculares hacia estadios precoces e identificar los pacientes con mínimos cambios estructurales y mayores probabilidades de remodelado inverso. Para hacer realidad este objetivo se necesita un parámetro capaz de detectar los cambios sutiles que se producen en el inicio de la enfermedad.En la actualidad la determinación de la fracción de eyección del ventrículo izquierdo (FEVI) es el método utilizado para medir la función sistólica, y aunque existe gran cantidad de literatura que respalda esta estrategia, hay varias limitaciones en la práctica diaria; por ejemplo, las técnicas empleadas para calcular la FEVI utilizan fórmulas con asunciones geométricas que no siempre son aplicables y sus resultados son muy susceptibles a cambios en la precarga, asimismo, la frecuencia cardíaca y las alteraciones del ritmo pueden dificultar mucho su interpretación (Marwick 2012). Al hablar de contractilidad regional el escenario se complica aún más. La correcta identificación de asimetrías regionales requiere un proceso de entrenamiento específico, así como la adquisición de experiencia, ya que este análisis es cualitativo, subjetivo y, como toda téc-nica ecocardiográfica, dependiente de la calidad de imagen disponible.Por todo esto es que la disponibilidad de una técni-ca para medir la función sistólica, como el análisis de deformación miocárdica, que sea cuantitativa, reproducible y fiable, supondría un avance considerable en la capacidad diagnóstica de la ecocardiografía actual. Para comprender este enfoque es necesario repasar dos conceptos: la arquitectura del ventrículo izquierdo y la transmuralidad de la enfermedad.Arquitectura del ventrículo izquierdo.-El conocimiento de la estructura miocárdica del ventrículo izquierdo (VI) es fundamental para comprender el estudio de la deformación, así como para optimizar el análisis de los parámetros de medición (Mor-Avi et al. 2011). Se ha descrito que los miocitos se encuentran dispuestos de manera que forman dos hélices continuas de fibras, pasando de una hélice orientada hacia la derecha en el subendocardio a una hélice orientada hacia la izquierda en el subepicardio, lo que ocasiona que el eje longitudinal de las fibras rote continuamente, y por consiguiente, sea distinto en cada capa de miocardio: longitudinal (respecto al eje del VI) en el subendocardio, circunferencial en el mesocardio y oblicua en el subepicardio (Sengupta et al. 2006). Esta distribución determina como cada región contribuye a la mecánica miocár-dica, por ejemplo, la deformación longitudinal se da gracias a las fibras subendocárdicas. El análisis de la deformación de las fibras según su orientación ha permitido definir los patrones de mecánica longitudinal, circunferencial, radial y de torsión (Opdahl et al. 2015).

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Population-Based Reference Values for 3D Echocardiographic LV Volumes and Ejection Fraction

Cited by 86 publications

References 13 publications

Adverse Left Ventricular Remodeling and Age Assessed with Cardiac MR Imaging: The Multi-Ethnic Study of Atherosclerosis

Adverse Left Ventricular Remodeling and Age Assessed with Cardiac MR Imaging: The Multi-Ethnic Study of Atherosclerosis

Adult echocardiographic nomograms: overview, critical review and creation of a software for automatic, fast and easy calculation of normal values

Ecocardiografía avanzada: aplicación clínica actual del análisis de deformación miocárdica y de la imagen tridimensional

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