Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control: 10-Year Results From the Oxford Vascular Study

Abstract

Conclusions: Hospital-based registries likely underestimate not only the incidence of acute aortic dissection but also its association with premorbid hypertension. The most significant treatable condition leading to acute aortic dissection remains uncontrolled hypertension.Summary: Even with well-established treatment guidelines, acute aortic dissection can have a high case fatality rate. However, little data on risk factors, incidence, or outcome of acute aortic dissection are available, and there is no prospective population-based study. Although abdominal aortic aneurysm incidence of rupture appears to be declining (Darwood R et al, J Vasc Surg 2012;56:8-13), trends with respect to acute aortic dissection are uncertain (Thrumurthy SG et al, BMJ 2012;344:d8290). The authors note there have only been two studies of the epidemiology of aortic dissection since 1980, and both were retrospective and used only routinely collected diagnostic or mortality coding data. Neither study assessed premorbid risk factors or functional outcome (

Aortic Dissection - The Role of Echocardiography in Emergency Unit: Case Report

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Warning at emergency room: The role of diagnostic test in acute aortic dissection

“…In the Oxford Vascular study, its incidence is estimated at six per hundred thousand persons per year. This incidence is higher in men than in women and increases with age [3][4][5].…”

Morphologic Characteristics for Treatment Guidance in Uncomplicated Acute Type B Aortic Dissection

“…[1][2][3] Patients with acute aortic dissection (AoD) can present with a variety of signs and symptoms that mimic other more common disease modalities. Therefore, a high index of suspicion is warranted in patients at risk for AoD, such as those with hypertension, use of cocaine or other stimulants, a family history of thoracic aneurysm or AoD, presence of genetic collagen-vascular disorders (eg, Marfan or Ehlers-Danlos syndrome), and inflammatory vasculitides (eg, Takayasu or giant cell arteritis).…”