Population-based Trends in Healthcare Utilization and National Healthcare Spending on Pancreatitis in North America

Ahmed, Newaz Shubidito; Forbes, Nauzer; Stukalin, Igor; Singh, Siddharth; Shaheen, Abdel Aziz; Ma, Christopher

doi:10.1053/j.gastro.2021.08.022

Cited by 7 publications

(6 citation statements)

References 8 publications

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“…A study by Habka et al [ 41 ] in 2015 predicted that the cost of LT will increase by 33% in 10 years and 81% in the next 20 years. The inpatient cost of management of AP has also almost doubled from 1996 ($3.9 billion) to 2016 ($7.7 billion)[ 42 ]. On the contrary, the utilization of the inpatient service (bed days per prevent case) for AP has declined over the years[ 42 ].…”

Section: Discussionmentioning

confidence: 99%

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Acute pancreatitis in liver transplant hospitalizations: Identifying national trends, clinical outcomes and healthcare burden in the United States

Dahiya,

Jahagirdar,

Chandan

et al. 2023

World J Hepatol

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BACKGROUND Acute pancreatitis (AP) in liver transplant (LT) recipients may lead to poor clinical outcomes and development of severe complications. AIM We aimed to assess national trends, clinical outcomes, and the healthcare burden of LT hospitalizations with AP in the United States (US). METHODS The National Inpatient Sample was utilized to identify all adult (≥ 18 years old) LT hospitalizations with AP in the US from 2007–2019. Non-LT AP hospitalizations served as controls for comparative analysis. National trends of hospitalization characteristics, clinical outcomes, complications, and healthcare burden for LT hospitalizations with AP were highlighted. Hospitalization characteristics, clinical outcomes, complications, and healthcare burden were also compared between the LT and non-LT cohorts. Furthermore, predictors of inpatient mortality for LT hospitalizations with AP were identified. All P values ≤ 0.05 were considered statistically significant. RESULTS The total number of LT hospitalizations with AP increased from 305 in 2007 to 610 in 2019. There was a rising trend of Hispanic (16.5% in 2007 to 21.1% in 2018, P-trend = 0.0009) and Asian (4.3% in 2007 to 7.4% in 2019, p-trend = 0.0002) LT hospitalizations with AP, while a decline was noted for Blacks (11% in 2007 to 8.3% in 2019, P-trend = 0.0004). Furthermore, LT hospitalizations with AP had an increasing comorbidity burden as the Charlson Comorbidity Index (CCI) score ≥ 3 increased from 41.64% in 2007 to 62.30% in 2019 (P-trend < 0.0001). We did not find statistically significant trends in inpatient mortality, mean length of stay (LOS), and mean total healthcare charge (THC) for LT hospitalizations with AP despite rising trends of complications such as sepsis, acute kidney failure (AKF), acute respiratory failure (ARF), abdominal abscesses, portal vein thrombosis (PVT), and venous thromboembolism (VTE). Between 2007–2019, 6863 LT hospitalizations with AP were compared to 5649980 non-LT AP hospitalizations. LT hospitalizations with AP were slightly older (53.5 vs 52.6 years, P = 0.017) and had a higher proportion of patients with CCI ≥ 3 (51.5% vs 19.8%, P < 0.0001) compared to the non-LT cohort. Additionally, LT hospitalizations with AP had a higher proportion of Whites (67.9% vs 64.6%, P < 0.0001) and Asians (4% vs 2.3%, P < 0.0001), while the non-LT cohort had a higher proportion of Blacks and Hispanics. Interestingly, LT hospitalizations with AP had lower inpatient mortality (1.37% vs 2.16%, P = 0.0479) compared to the non-LT cohort despite having a higher mean age, CCI scores, and complications such as AKF, PVT, VTE, and the need for blood transfusion. How...

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Section: Discussionmentioning

confidence: 99%

“…The inpatient cost of management of AP has also almost doubled from 1996 ($3.9 billion) to 2016 ($7.7 billion)[ 42 ]. On the contrary, the utilization of the inpatient service (bed days per prevent case) for AP has declined over the years[ 42 ]. No data currently exists on healthcare utilization for AP in LT recipients.…”

Section: Discussionmentioning

confidence: 99%

Acute pancreatitis in liver transplant hospitalizations: Identifying national trends, clinical outcomes and healthcare burden in the United States

Dahiya,

Jahagirdar,

Chandan

et al. 2023

World J Hepatol

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“…The methods used in this article are described in detail in our previous publications. 14,15 In brief, this study used public data from the Disease Expenditure Project 2016 (DEX 2016) and the Global Burden of Disease Study 2019 (GBD 2019), both of which were the most recently available data.…”

Section: Data Sourcesmentioning

confidence: 99%

Trends in health care spending on kidney cancer in the United States, 1996–2016

Takemura

Ahmed

Stukalin

et al. 2023

Cancer

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Background: Paradigm shifts in kidney cancer management have led to higher health care spending. Here, total and per capita health care spending and primary drivers of change in health expenditures for kidney cancer in the United States between 1996 and 2016 are estimated. Methods: Public databases developed by the Institute for Health Metrics and Evaluation for the Disease Expenditure Project were used. The prevalence of kidney cancer was estimated from the Global Burden of Disease Study. Changes in health care spending on kidney cancer were assessed by joinpoint regression and expressed as annual percent changes (APCs).

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“…Since the 1990s, healthcare spending for acute pancreatitis has nearly doubled. 1 Lacking healthcare coverage is associated with an increased rate of cardiovascular disease mortality, increased risk of distant oncologic disease across all types of malignancies, and increased risk of end-stage renal disease and mortality in patients with underlying chronic kidney disease. [2][3][4][5] Given that acute pancreatitis is associated with significant morbidity and mortality, we evaluated the association between healthcare coverage prevalence and acute pancreatitis mortality rates.…”

Section: Dear Editormentioning

confidence: 99%

Health insurance prevalence and acute pancreatitis mortality: a cross-sectional analysis

Loveland,

Le Cam,

Ibrahim

et al. 2023

Journal of Investigative Medicine

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Population-based Trends in Healthcare Utilization and National Healthcare Spending on Pancreatitis in North America

Cited by 7 publications

References 8 publications

Acute pancreatitis in liver transplant hospitalizations: Identifying national trends, clinical outcomes and healthcare burden in the United States

Acute pancreatitis in liver transplant hospitalizations: Identifying national trends, clinical outcomes and healthcare burden in the United States

Trends in health care spending on kidney cancer in the United States, 1996–2016

Health insurance prevalence and acute pancreatitis mortality: a cross-sectional analysis

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