Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit

Tao, Ruiyang; Dong, Xinyu; Zhen, Xiaoyuan; Xia, Ruocheng; Qu, Yiling; Liu, Shiquan; Zhang, Suhua; Li, Chengtao

doi:10.1007/s00438-024-02121-w

Mol Genet Genomics

2024

DOI: 10.1007/s00438-024-02121-w

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Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit

Ruiyang Tao,

Xinyu Dong,

Xiaoyuan Zhen

et al.

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Cited by 2 publications

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Characterisation of identity-informative genetic markers in the Australian population with European ancestry

Watson,

Cho,

Grisedale

et al. 2025

Forensic Science International: Genetics

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Characterisation of identity-informative genetic markers in the Australian population with European ancestry

Watson,

Cho,

Grisedale

et al. 2025

Forensic Science International: Genetics

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Applications and Performance of Precision ID GlobalFiler NGS STR, Identity, and Ancestry Panels in Forensic Genetics

Pedroza Matute,

Iyavoo

2024

Genes

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Short Tandem Repeat (STR) testing via capillary electrophoresis is undoubtedly the most popular forensic genetic testing method. However, its low multiplexing capabilities and limited performance with challenging samples are among the factors pushing scientists towards new technologies. Next-generation sequencing (NGS) methods overcome some of these limitations while also enabling the testing of Single-Nucleotide Polymorphisms (SNPs). Nonetheless, these methods are still under optimization, and their adoption into practice is limited. Among the available kits, Thermo Fisher Scientific (Waltham, MA, USA) produces three Precision ID Panels: GlobalFiler NGS STR, Identity, and Ancestry. A clear review of these kits, providing information useful for the promotion of their use, is, however, lacking. To close the gap, a literature review was performed to investigate the popularity, applications, and performance of these kits. Following the PRISMA guidelines, 89 publications produced since 2015 were identified. China was the most active country in the field, and the Identity Panel was the most researched. All kits appeared robust and useful for low-quality and low-quantity samples, while performance with mixtures varied. The need for more population data was highlighted, as well as further research surrounding variables affecting the quality of the sequencing results.

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Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit

Cited by 2 publications

References 46 publications

Characterisation of identity-informative genetic markers in the Australian population with European ancestry

Characterisation of identity-informative genetic markers in the Australian population with European ancestry

Applications and Performance of Precision ID GlobalFiler NGS STR, Identity, and Ancestry Panels in Forensic Genetics

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