Abstract:Human
NAT1
gene for
N
-acetyltransferase 1 modulates xenobiotic metabolism of arylamine drugs and mutagens. Beyond pharmacogenetics,
NAT1
is also relevant to breast cancer. The population history of human
NAT1
suggests evolution through purifying selection, but it is unclear whether this pattern is evident in other primate lineages where population studies are scarce. We report
NAT1
polymorphism i… Show more
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