2022
DOI: 10.1103/physrevapplied.17.024032
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Pore Dynamics of Lipid Vesicles Under Light-Induced Osmotic Stress

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Cited by 3 publications
(2 citation statements)
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“…While the smFRET approach provides details of vesicle perturbation on the nanoscale, a limitation is that it does not quantitatively report on pore formation or solution exchange across the bilayer. Recent studies on GUVs have provided evidence to support the transient formation of nanoscale pores induced by osmotic pressure and variations in membrane tension ( Shibly et al, 2016 ; Billah et al, 2022 ; Malik et al, 2022 ). While we obtained limited evidence for the formation of pores induced by sorbitol ( Figure 3S ), whether this is also true for the sub-micron-sized vesicles in response to PEG-based crowders remains an open question.…”
Section: Resultsmentioning
confidence: 99%
“…While the smFRET approach provides details of vesicle perturbation on the nanoscale, a limitation is that it does not quantitatively report on pore formation or solution exchange across the bilayer. Recent studies on GUVs have provided evidence to support the transient formation of nanoscale pores induced by osmotic pressure and variations in membrane tension ( Shibly et al, 2016 ; Billah et al, 2022 ; Malik et al, 2022 ). While we obtained limited evidence for the formation of pores induced by sorbitol ( Figure 3S ), whether this is also true for the sub-micron-sized vesicles in response to PEG-based crowders remains an open question.…”
Section: Resultsmentioning
confidence: 99%
“…While the smFRET approach provides details of vesicle perturbation on the nanoscale, a limitation is that it does not quantitatively report on pore formation or solution exchange across the bilayer. Recent studies on GUVs have provided evidence to support the transient formation of nanoscale pores induced by osmotic pressure and variations in membrane tension 54-56 . While we obtained limited evidence for the formation of pores induced by sorbitol ( Figure 3S ), whether this is also true for the sub-micron sized vesicles in response to PEG-based crowders remains an open question.…”
Section: Resultsmentioning
confidence: 99%