Porocarcinoma écrino: relato de quatro casos e revisão da literatura

Abstract

Resumo: Porocarcinoma écrino é um tumor de pele raro derivado do acrossiríngeo. Quatro casos de porocarcinoma écrino são estudados. Os pacientes tinham idade entre 49 e 64 anos, sendo dois homens e duas mulheres. O tempo de crescimento dos tumores variou de um a 20 anos. As lesões mediam de 1,2 x 2 a 4 x 5 cm e se localizavam nas extremidades ou na face. Dois pacientes apresentavam carcinoma basocelular em sítios diferentes do porocarcinoma écrino. Duas das biópsias foram previamente descritas como poroma écrino; entretanto, malignidade foi observada em todos os casos após excisão ampla. Portanto, em toda biópsia de pele compatível com poroma écrino, deve-se considerar a possibilidade de malignidade. Palavras-chave: Acrospiroma écrino; Adenocarcinoma; Carcinoma; Glândulas Abstract: Eccrine porocarcinoma is an extremely rare skin tumor derived from the acrosyringium. Four cases of eccrine porocarcinoma are described, two males and two females, aged from 49 to 64 years. Tumors grew in an interval of one to 20 years. Lesions ranged from 1.2 x 2 cm to 4 x 5 cm and were on limbs or face. Two patients had basal cell carcinoma in a site different from the eccrine porocarcinoma. Two biopsies were described as eccrine poroma. Malignancy was observed in all cases after wide excision. Therefore, eccrine porocarcinoma should always be considered after a biopsy compatible with eccrine poroma. Keywords: Acrospiroma, eccrine; Adenocarcinoma; Carcinoma; Eccrine glands INTRODUÇÃOOs carcinomas das glândulas sudoríparas são raros, compreendendo cerca de 0,005% de todas as neoplasias da pele.1 O porocarcinoma écrino (PCE) ou poroma écrino maligno é um tumor de pele extremamente raro, embora seja relativamente comum ao se considerarem os carcinomas de glândulas sudorí-paras. Surge da porção intraepitelial da unidade da glândula sudorípara écrina, o acrossiríngio, podendo apresentar-se como tumor primário ou, mais comumente, como uma transformação maligna de um poroma écrino (PE).2 A primeira descrição do tumor foi em 1963 por Pinkus e Mehregan.

Eccrine porocarcinoma in the tempus of an elderly woman: A case report

“…The most common location of presentation is the head and neck (39.9%), followed by the lower extremities (33.9%)[ 6 ]. Similar to our case, EPC has been reported in the left temporal area, with the appearance of a verrucous lesion[ 7 ]. However, the tumors had a longer growth time (one year to twenty years)[ 7 ] than that in our case (four months).…”

Pigmented eccrine poroma: report of an atypical case with the use of dermoscopy

“…3 There is a malignant variant, the porocarcinoma, which may be a primary tumor, but generally results from the malignant transformation of EP. 7 Approximately 8% of cases present as multiple lesions, named poromatosis. 3 The lesions tend to be asymptomatic and, in roughly 50% of cases, are located in the plantar region.…”

Porocarcinoma: relato de caso

“…2,7,8, As also reported in the Mulinari-Brenner and cols review, the lesions varied between 1.2 x 2.0 and 4 x 5 cm. 9 In the case presented, the lesion was extensive, affecting the entire anterior thorax, a less common region, seen in 24% of the cases described in the literature. 10 The most affected locations, in 44% of cases, are the lower limbs, with 11% for the leg and 10% for the feet.…”