Porocarcinoma of the Eyelid

Mohs Micrographic Surgery for Eccrine Porocarcinoma

“…42 Treatment, Prognosis, and Follow-ups Currently, wide local excision (WLE) with broad tumor margins seems to be the most widely used treatment, with curative rates from 70% to 80% of cases. Three more reports published in 1990s presented 7 cases of EPC treated with MMS without any evidence of recurrence, [24][25][26] with an average follow-up length of 23 months (range, 5-48 months). 14,31,39 Other treatments including chemotherapy, 44,45 single-agent or multiagent chemotherapy with isotretinoin, 46 interferon alfa, 47 radiation therapy (usually as adjuvant postoperative palliative care), 48 and electroporation (intralesional chemotherapy) have also been reported as being well tolerated but with varying responses.…”

“…[14][15][16] Given the rarity of this neoplasm, an optimal treatment regimen has not yet been established. 4,[23][24][25][26][27][28][29][30][31][32] In addition to a comprehensive review of the literature, the authors report the second case of MMS-treated EPC on the temple, and the 21st case of EPC successfully treated with MMS. Mohs micrographic surgery has been shown to be an effective therapy for many uncommon malignant cutaneous tumors, 17 including rare adnexal tumors such as sebaceous carcinoma, 18 microcystic adnexal carcinoma, 19,20 pilomatrix carcinoma, 21 and desmoplastic trichilemmoma.…”

Eccrine Porocarcinoma Treated with Mohs Micrographic Surgery: A Report of Five Cases

“…The first case of a malignant variant was subsequently reported and termed epidermotropic eccrine carcinoma. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Eccrine porocarcinoma is a locally aggressive tumor that has the potential to metastasize. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Eccrine porocarcinoma is a locally aggressive tumor that has the potential to metastasize.…”

Eccrine poroma of the eyelid

“…To our knowledge, an eyelid benign eccrine poroma has never been reported, although Boynton and Markowitch recently described a case of the malignant counterpart, eccrine porocarcinoma, which had arisen de novo 4 . Several large retrospective studies of eyelid lesions have not reported any cases of eccrine poromas 4–6 …”