Porokeratosis ptychotropica responding to photodynamic therapy: An alternative treatment for a refractory disease

Abstract

PDT seems to be a good therapeutic alternative in the treatment of PP, as it can provide symptomatic relief and clinical improvement of the lesions. However, it does not appear to be a curative treatment. Moreover, long-term response is still unknown.

Perineal warty plaques

“…[ 11 ] Photodynamic therapy was found to be useful as an alternative treatment, but its utility remains limited to providing symptomatic relief in itch and partial clearance of lesion, and it did not achieve curative response. [ 12 ] Smaller lesions can be approached for surgical intervention as has been shown in a few case reports, but it is difficult to comment upon the rate of recurrence on the basis of only these few. [ 13 ] Further studies are required to ascertain the role and prognosis of surgery in verrucous porokeratosis.…”

Improvements in two subtypes of porokeratosis by superficial X‐ray radiotherapy

“…used to treat the skin disorder with conflicting results. 2,4 Although photodynamic therapy has shown efficacy in recent cases, 5 its application is limited because of its high cost and the painful experience of patients. Thus, we attempted a novel treatment regimen for both patients.…”

Porokeratosis Ptychotropica on the Penis and Scrotum: A Case Report

“…No standard treatment has been reported that shows complete clearance. Photodynamic therapy can be used as a therapeutic alternative treatment (8). Surgical approaches can be considered as an option for smal-ler lesions.…”