Porous biomimetic membranes: fabrication, properties and future applications

Abstract

A cell membrane is a flexible lipid bilayer with sophisticated functions which dominate the exchange of material, energy and information between the outside and the inside of the cell. In order to understand and imitate these structures and functions, scientists had already developed a variety of mimic membranes which are alike in form based on lipid bilayer and organic channel-molecules. With the rise of nanotechnology, a large number of synthetic nano-devices are widely used to construct porous biomimetic membranes which are alike in spirit instead of the conventional lipid bilayer membranes. This perspective will first introduce several typical methods to fabricate porous biomimetic membranes, and then discuss the "smart" properties and future applications of these membranes in materials transport, energy transformation and signal transduction aspects.

Self‐Assembly Behavior and Application of Terphenyl‐Cored Trimaltosides for Membrane‐Protein Studies: Impact of Detergent Hydrophobic Group Geometry on Protein Stability

“…Detailed intermolecular interactions driving these self-assembly formationsw ere addressed via chemical shift analysis using 1 HNMR spectroscopy. [34,35] When dissolved in CD 3 OD at room temperature, TPM-L3 showeds ix well-resolveds ignals in a range of 7.74 to 6.99 ppm, corresponding to the aromatic protons (Figure 3a,t op).…”

“…Biomimetic materials capable of reproducing the architecture and properties of native biological membranes are attracting much interest in the field of biomedical sciences . Some natural or synthetic amphiphiles can simulate the behavior of cell membrane components by self‐assembling into organized structures in aqueous environments .…”

“…Biomimetic materials capableo fr eproducing the architecture and properties of native biological membranes are attracting much interest in the field of biomedical sciences. [1,2] Some natural or synthetic amphiphilesc an simulatet he behavior of cell membrane components by self-assemblingi nto organized structures in aqueouse nvironments. [3,4] Self-assembled structures formed by amphiphiles varyf rom simple micelles to highlyo rganized large aggregates such as fibers, tubes, and helices, and are increasingly used in materialc hemistry,n anotechnology,a nd medicinal chemistry.…”

Fabrication of Biomimetic and Bioinspired Membranes

“…There is a substantial number of channels formed by proteins, as well as protein assemblies, within the cell's membrane and that effectively contribute to the transmembrane transport of water, nutrients, and ions [6,87]. The rapid and relatively controllable transport of water, ions, and other nutrients through biological channels ensures the success of their essential movements within the organisms [6,9,88,89]. Currently, the process of simulating the biological channels' structure of in cell membranes with the aim of producing artificial membranes, offering high performance and a range of useful functions, has been of enormous technological and scientific interest.…”

Glycosylated membranes: A promising biomimetic material

“…In the recent years, biomimetic membrane research has been paid much attention due to the requirements of other technologies, especially in biotechnology. [11][12][13] Among all of the studies for biomimetic membranes, glycosylated membrane is a promising one which has been rapidly developed in the last 10 years. [14][15][16][17][18] As the name implies, the glycosylated membrane is one of the developing biomimetic membranes, which combines the separation functionality of membranes with the biological functionality of cell surface saccharides.…”