Porous c.p. Titanium Using Dextrin as Space Holder for Endosseous Implants

Gligor, Ionuţ; Şoriţău, Olga; Todea, M.; Berce, Cristian; Vulpoi, Adriana; Marcu, Teodora; Cernea, Valentin; Simon, S.; Popa, Cătălin

doi:10.1080/02726351.2012.749556

Cited by 24 publications

(17 citation statements)

References 21 publications

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“…Porosity, As compared to those of other space holder materials such as sodium chloride [9], dextrin [16] and saccharose [13], the voids have higher sphericity, are more uniform in shape and are homogenously distributed in the sample with high interconnectivity.…”

Section: Resultsmentioning

confidence: 99%

Manufacturing of biocompatible porous titanium scaffolds using a novel spherical sugar pellet space holder

et al. 2017

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. removed by dissolution in water before sintering. The morphology, pore structure and porosity were observed by optical microscopy, SEM and micro-CT. The porous titanium has highly spherical pore shapes, well-controlled pore sizes and high interconnectivity.The results suggest that porous titanium scaffolds generated using this manufacturing route have the potential for hard tissue engineering applications.

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Section: Resultsmentioning

confidence: 99%

Manufacturing of biocompatible porous titanium scaffolds using a novel spherical sugar pellet space holder

et al. 2017

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“…Particularly, a porous structure can be adjusted to resemble that of bone. 22 The elasticity modulus can also affect survival of implants. 23 A low Young modulus results in more micromotion, which produces fibrous tissue instead of bone at the bone–implant interface.…”

Section: Titanium In Medical Applicationsmentioning

confidence: 99%

Current methods of preventing aseptic loosening and improving osseointegration of titanium implants in cementless total hip arthroplasty: a review

Apostu¹,

et al. 2017

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Hip osteoarthritis is the most common joint disorder, and is represented by a degenerative process, resulting in pain and functional impairment. If conservative treatment for hip osteoarthritis fails, the only remaining option is hip arthroplasty. Despite good survival of implants, loosening of components is the most common complication. This leads to revision surgeries, which are technically demanding, expensive, and result in a low satisfaction rate. Uncemented hip replacements require proper osseointegration for increased survival. Physical characteristics of implants include biocompatibility, Young’s modulus of elasticity, strength, and corrosion resistance, and each influence fixation of implants. Moreover, implant surface treatments, pore size, pore density, and femoral stem design should be appropriately selected. Patients’ optimization of obesity, osteoporosis, cardiovascular disease, psychotic disorders, and smoking cessation are associated with a higher survival of implants. Surgical factors, such as approach, drilling and rasping, acetabular bone coverage, acetabular cup positioning, and implant size, also affect survival of implants. Avoiding drugs, which may impair osseointegration of implants, and having an appropriate rehabilitation protocol are important. Future directions include anabolic and anti-catabolic bone-acting drugs to enhance osseointegration of implants. Comprehensive knowledge of the factors mentioned above is important for preventing aseptic loosening, with important socioeconomic consequences.

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“…In addition, food-grade powders, such as sodium chloride [35,36,55,73,74], saccharose [39], dextrin corn starch [38] and tapioca starch [37] have been devised as safe space holders. Reactions between matrix powder and space-holding particles or binder must be avoided and hence chemically stable space-holding particles are preferred.…”

Section: Powder Selection and Preparationmentioning

confidence: 99%

Fabrication of Metallic Biomedical Scaffolds with the Space Holder Method: A Review

2014

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Bone tissue engineering has been increasingly studied as an alternative approach to bone defect reconstruction. In this approach, new bone cells are stimulated to grow and heal the defect with the aid of a scaffold that serves as a medium for bone cell formation and growth. Scaffolds made of metallic materials have preferably been chosen for bone tissue engineering applications where load-bearing capacities are required, considering the superior mechanical properties possessed by this type of materials to those of polymeric and ceramic materials. The space holder method has been recognized as one of the viable methods for the fabrication of metallic biomedical scaffolds. In this method, temporary powder particles, namely space holder, are devised as a pore former for scaffolds. In general, the whole scaffold fabrication process with the space holder method can be divided into four main steps: (i) mixing of metal matrix powder and space-holding particles; (ii) compaction of granular materials; (iii) removal of space-holding particles; (iv) sintering of porous scaffold preform. In this review, detailed procedures in each of these steps are presented. Technical challenges encountered during scaffold fabrication with this specific method are addressed. In conclusion, strategies are yet to be developed to address problematic issues raised, such as powder segregation, pore inhomogeneity, distortion of pore sizes and shape, uncontrolled shrinkage and contamination.

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Porous c.p. Titanium Using Dextrin as Space Holder for Endosseous Implants

Cited by 24 publications

References 21 publications

Manufacturing of biocompatible porous titanium scaffolds using a novel spherical sugar pellet space holder

Manufacturing of biocompatible porous titanium scaffolds using a novel spherical sugar pellet space holder

Current methods of preventing aseptic loosening and improving osseointegration of titanium implants in cementless total hip arthroplasty: a review

Fabrication of Metallic Biomedical Scaffolds with the Space Holder Method: A Review

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