Porous Carbon Materials in Biomedical Applications

Thambiliyagodage, Charitha; Mirihana, Shanitha; Gunathilaka, Himasha

doi:10.26717/bjstr.2019.22.003798

Cited by 9 publications

(6 citation statements)

References 24 publications

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“…Porous materials find applications in a plethora of different key fields, such as the sorption and storage of chemicals, ion exchange, catalysis, filters, biomedicine and drug-delivery systems, and thermal and acoustic insulation [ 174 , 175 , 176 , 177 , 178 , 179 , 180 ]. They present large SSAs, with many active sites available for the functionalization with molecules [ 181 , 182 , 183 , 184 ].…”

Section: Application Of Waste-derived Silicamentioning

confidence: 99%

“…According to the International Union of Pure and Applied Chemistry (IUPAC), microporous materials have a pore size smaller than the 2 nm range and mesoporous materials in the 2-50 nm range; macroporous materials have a pore size larger than 50 nm (Figure 5) [174,175]. Porous materials find applications in a plethora of different key fields, such as the sorption and storage of chemicals, ion exchange, catalysis, filters, biomedicine and drugdelivery systems, and thermal and acoustic insulation [174][175][176][177][178][179][180]. They present large SSAs, with many active sites available for the functionalization with molecules [181][182][183][184].…”

Section: Porous Waste-derived Silicamentioning

confidence: 99%

“…Herein, the morphology of the final material was directly determined by rigid templates, removed by carbonization or acid treatments, assuring uniformity in the porous structure [185][186][187][188]. Porous materials find applications in a plethora of different key fields, such as the sorption and storage of chemicals, ion exchange, catalysis, filters, biomedicine and drugdelivery systems, and thermal and acoustic insulation [174][175][176][177][178][179][180]. They present large SSAs, with many active sites available for the functionalization with molecules [181][182][183][184].…”

Section: Porous Waste-derived Silicamentioning

confidence: 99%

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Recent Advances on Porous Siliceous Materials Derived from Waste

Montini,

Cara,

D’Arienzo

et al. 2023

Materials

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In recent years, significant efforts have been made in view of a transition from a linear to a circular economy, where the value of products, materials, resources, and waste is maintained as long as possible in the economy. The re-utilization of industrial and agricultural waste into value-added products, such as nanostructured siliceous materials, has become a challenging topic as an effective strategy in waste management and a sustainable model aimed to limit the use of landfill, conserve natural resources, and reduce the use of harmful substances. In light of these considerations, nanoporous silica has attracted attention in various applications owing to the tunable pore dimensions, high specific surface areas, tailorable structure, and facile post-functionalization. In this review, recent progress on the synthesis of siliceous materials from different types of waste is presented, analyzing the factors influencing the size and morphology of the final product, alongside different synthetic methods used to impart specific porosity. Applications in the fields of wastewater/gas treatment and catalysis are discussed, focusing on process feasibility in large-scale productions.

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Section: Application Of Waste-derived Silicamentioning

confidence: 99%

Section: Porous Waste-derived Silicamentioning

confidence: 99%

Section: Porous Waste-derived Silicamentioning

confidence: 99%

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Recent Advances on Porous Siliceous Materials Derived from Waste

Montini,

Cara,

D’Arienzo

et al. 2023

Materials

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“…Over recent years, several multicomponent metal-oxide-based nanostructures have been explored. , In this regard, carbon nanomaterials like porous carbon materials, reduced graphene oxide (rGO), carbon nanotubes (CNTs), and metal oxides have been extensively used in the discipline of biomedicine and pharmacology. But on the other side, scientists focused on porous materials because their design of tunable pores has been shown to exhibit exceptional impacts in bioactivities and drug delivery systems .…”

Section: Introductionmentioning

confidence: 99%

Bioderived Mesoporous Carbon@Tungsten Oxide Nanocomposite as a Drug Carrier Vehicle of Doxorubicin for Potent Cancer Therapy

Bhosale

Patil

et al. 2023

Langmuir

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Scientists have investigated the possibility of employing nanomaterials as drug carriers. These nanomaterials can preserve their content and transport it to the target region in the body. In this investigation, we proposed a simple method for developing distinctive, bioderived nanostructures with mesoporous carbon nanoparticles impregnated with tungsten oxide (WO 3 ). Prior to characterizing and encapsulating WO 3 with bioderived mesoporous carbon, the anticancer drug doxorubicin (DOX) was added to the nanoparticles and examined loading and release study. The approaches for both nanoparticle production and characterization are discussed in detail. Colloidal qualities of the nanomaterial can be effectively preserved while also allowing transdermal transportation of nanoparticles into the body by forming them into green, reusable, and porous nanostructures. Although the theories of nanoparticles and bioderived carbon each have been studied separately, the combination presents a new route to applications connected to nanomedicine. Furthermore, this sample was used to study exotic biomedical applications, such as antioxidant, antimicrobial, and anticancer activities. The W-3 sample had lower antioxidant activity (44.01%) than the C@W sample (56.34%), which was the most potent. A high DOX entrapment effectiveness of 97% was eventually achieved by the C@W sample, compared to a pure WO 3 entrapment efficiency of 91%. It was observed that the Carbon/WO 3 composite (C@W) sample showed more efficacy because the mesoporous carbon composition with WO 3 increases the average surface area and surface-active locations.

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“…[14][15][16][17] The ability to control the porous structure and characteristics of the carbon surface of sorbents allows immobilization of biologically active or medicinal substances. [18][19][20][21] One of the carbon sorbents is the mesoporous carbon sorbent VNIITU-2, developed at the Center of New Chemical Technologies of the Federal Research Center Boreskov Institute of Catalysis, Siberian Branch of the Russian Academy of Sciences (Omsk Branch). A specially developed technology for obtaining a sorbent, consisting of several stages, makes it possible to obtain a chemically pure sorbent with a carbon content of at least 99.5%, and a total ash of not more than 0.5%.…”

Section: Introductionmentioning

confidence: 99%

Applicability of modified carbon sorbent for removing potentially toxic biologically active molecules of aromatic structure from blood plasma

et al. 2021

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The modification of the mesoporous carbon sorbent with 3-phenylpropanoic acid was carried out in order to create preparations of complex, prolonged action, exhibiting detoxifying, antibacterial, and antifungal properties due to the applied modifier, which is capable of migrating into the solution and exhibiting its own biospecific properties. A technique was developed for fixing 3-phenylpropionic acid (PhPA) on a carbon support by its adsorption from solution. Three types of sorbents with various content of the modifier (PhPA) and the sorbent without modifier were studied. The sorption activity of new sorbents was studied using liquid-liquid extraction and gas chromatography-mass spectrometry methods on model experiments with plasma and aqueous additives of hydroxylated phenyl-containing acids (PhCAs) in various concentrations. The specific surface area was significantly changed for sorbent, modified with 1 × 10−3 mol/L of PhPA solution, and was 25% less than the area of unmodified sorbent. Potentially toxic biologically active hydroxylated PhCAs were used to create model solutions. The degrees of sorption of these compounds were close to 100%, except phenyllactic acid (over 80%). The sorbent without modifier and two sorbents with the lowest content of the modifier are considered to be more effective for the purification of the plasma from the hydroxylated PhCAs than the sorbent with the highest concentration of the modifier. Simultaneous adsorption of toxic metabolites from the bloodstream and desorption of beneficial ones can be used for a more subtle correction of the patient’s condition.

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Porous Carbon Materials in Biomedical Applications

Cited by 9 publications

References 24 publications

Recent Advances on Porous Siliceous Materials Derived from Waste

Recent Advances on Porous Siliceous Materials Derived from Waste

Bioderived Mesoporous Carbon@Tungsten Oxide Nanocomposite as a Drug Carrier Vehicle of Doxorubicin for Potent Cancer Therapy

Applicability of modified carbon sorbent for removing potentially toxic biologically active molecules of aromatic structure from blood plasma

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