Porous Media Applications: Biological Systems

Shape memory polymer (SMP) foam is often proposed as the future alternative of coils in aneurysm treatment devices. Present work numerically investigates the unsteady, three-dimensional simulation of blood flow in a cerebral aneurysm filled with SMP foam. Simulations are conducted on patient-specific geometries with realistic blood velocity waveform imposed at the inlet while SMP foam is treated as a porous medium. The present study introduces a “loading risk map” that helps to visualize the hemodynamic effect of foam insertion on the aneurysm sac and neck. The loading risk maps suggest that while the SMP foam subdues the flow and wall shear pulsations in the aneurysm sac, the pressure distribution is minimally affected. The maps suggest that while the downstream lip is the most risk-prone site for both geometries, downstream vascular anatomy significantly influences foam efficiency in reducing pressure and wall shear stress loading.

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“…The present study uses two patient-specific geometries, 29,30 shown in Figure 1(a) and (b). The inlet diameter for both geometries is 4.5 mm.…”

Section: Geometrymentioning

confidence: 99%

Assessment and visualization of hemodynamic loading in aneurysm sac and neck: Effect of foam insertion

Pandey

Paul

Das

et al. 2021

Proc Inst Mech Eng H

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“…These geometries are reconstructed from magnetic resonance angiography (MRA) images. The patient-specific geometry is obtained as an open-source mesh from the CISTIB laboratory at Universitat Pompeu Fabra of Barcelona [43]. Using open-source tools, i.e., GIMIAS and VMTK, geometries are constructed as shown in Fig.…”

Section: Geometrymentioning

confidence: 99%

“…Using open-source tools, i.e., GIMIAS and VMTK, geometries are constructed as shown in Fig. 2(a) and 2(b) [43]. Next, meshes for these geometries are generated using a commercial grid generator, i.e., ICEM-CFD.…”

Section: Geometrymentioning

confidence: 99%

Effect of foam insertion in aneurysm sac on flow structures in parent lumen: relating vortex structures with disturbed shear

Pandey

Das

2021

Phys Eng Sci Med

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Numerous studies suggest that disturbed shear, causing endothelium dysfunction, can be related to neighboring vortex structures. With this motivation, this study presents a methodology to characterize the vortex structures. Precisely, we use mapping and characterization of vortex structures' changes to relate it with the hemodynamic indicators of disturbed shear. Topological features of vortex core lines (VCLs) are used to quantify the changes in vortex structures.We use the Sujudi-Haimes algorithm to extract the VCLs from the flow simulation results. The idea of relating vortex structures with disturbed shear is demonstrated for cerebral arteries with aneurysms virtually treated by inserting foam in the sac. To get physiologically realistic flow fields, we simulate blood flow in two patient-specific geometries before and after foam insertion, with realistic velocity waveform imposed at the inlet, using the Carreau-Yashuda model to mimic the shear-thinning behavior. With homogenous porous medium assumption, flow through the foam is modeled using the Forcheimmer-Brinkmann extended Darcy model. Results show that foam insertion increases the number of VCLs in the parent lumen. The average length of VCL increases by 168.9% and 55.6% in both geometries.For both geometries under consideration, results demonstrate that the region with increased disturbed shear lies in the same arterial segment exhibiting an increase in the number of oblique VCLs. Based on the findings, we conjecture that an increase in oblique VCLs is related to increased disturbed shear at the neighboring portion of the arterial wall.

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“…Fuller et al [15] conducted groundbreaking research examining the intercalation mechanism within electrodes and revealed that thinner cells are optimal in case of higher current density. Furthermore, Mukherjee et al [16] probed electrode kinetics and established a numerical model for cell performance prediction. Newman and team [15,[17][18][19] proposed a porous electrode model using a concentrated solution framework.…”

Section: Introductionmentioning

confidence: 99%

Tuning the Particle Size Distribution at Cathode for Enhanced Li-Ion Battery Performance

Kanchan,

Randive

2023

JNMES

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The Li-ion battery's diverse applications necessitate the quest to design energy and powerdense electrode microstructure. The present study uses the Doyle-Newman framework to probe the interplay of cathode particle size configurations for various current densities. Our study reveals the interplay of cathode particle size distribution and C-rate on cell performance characteristics. Further, the cell performs better when the cathode employs a cathode particle size configuration arranged non-uniformly. Moreover, the cell characteristics, viz. specific energy, specific power, and capacity, are highest for the configuration where the cathode particle size increases in the direction of the cathode current collector interface. Additionally, losses are relatively lesser in this configuration. Furthermore, the cell characteristics become more significant for higher current density. In addition, as particle size grows at a higher rate, the improvement in cell performance is significant. Our findings bear utility towards advancement in cathode on the microstructural scale and offer better spatiotemporal ionic transport kinetics.

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Porous Media Applications: Biological Systems

Cited by 6 publications

References 60 publications

Assessment and visualization of hemodynamic loading in aneurysm sac and neck: Effect of foam insertion

Assessment and visualization of hemodynamic loading in aneurysm sac and neck: Effect of foam insertion

Effect of foam insertion in aneurysm sac on flow structures in parent lumen: relating vortex structures with disturbed shear

Tuning the Particle Size Distribution at Cathode for Enhanced Li-Ion Battery Performance

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