Porous Particle-Polymer Composites

Alam, Parvez

doi:10.5772/18840

Cited by 3 publications

(2 citation statements)

References 86 publications

(64 reference statements)

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“…It is well known that an increase in polydispersity of particles leads to a decrease in void volume when the particles are packed [20]. This is also valid for porous particle-polymer composites [21]. Wider size distribution of the BG2 particles allows denser packing of the BG2 particles in the polymer matrix, resulting in relatively less porous composite films.…”

Section: Structural and Mechanical Characterisation Of Composite Scaf...mentioning

confidence: 89%

Modulation of neuronal cell affinity of composite scaffolds based on polyhydroxyalkanoates and bioactive glasses

et al. 2020

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The biocompatibility and neuron regenerating properties of various bioactive glass (BG)/polyhydroxyalkanoate (PHA) blend composites were assessed in order to study their suitability for peripheral nerve tissue applications, specifically as lumen structures for nerve guidance conduits. BG/PHA blend composites were fabricated using Bioactive glass® 45 S5 (BG1) and BG 1393 (BG2) with the 25:75 poly(3-hydroxyoctanoate/poly3-hydroxybutyrate), 25:75 P(3HO)/P(3HB) blend (PHA blend). Various concentrations of each BG (0.5 wt%, 1.0 wt% and 2.5 wt%) were used to determine the effect of BG on neuronal growth and differentiation, in single culture using NG108-15 neuronal cells and in a co-culture along with RN22 Schwann cells. NG108-15 cells exhibited good growth and differentiation on all the PHA blend composites showing that both BGs have good biocompatibility at 0.5 wt%, 1.0 wt% and 2.5 wt% within the PHA blend. The Young’s modulus values displayed by all the PHA blend/BG composites ranged from 385.6 MPa to 1792.6 MPa, which are able to provide the required support and protective effect for the regeneration of peripheral nerves. More specifically, the tensile strength obtained in the PHA blend/BG1 (1.0 wt%) (10.0 ± 0.6 MPa) was found to be similar to that of the rabbit peroneal nerve. This composite also exhibited the best biological performance in supporting growth and neuronal differentiation among all the substrates. The neurite extension on this composite was found to be remarkable with the neurites forming a complex connection network.

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Section: Structural and Mechanical Characterisation Of Composite Scaf...mentioning

confidence: 89%

Modulation of neuronal cell affinity of composite scaffolds based on polyhydroxyalkanoates and bioactive glasses

et al. 2020

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“…The change in the fractional composition from the optimal ratio (for the selected fractions of the Normcal-2 and Normcal-100 microfillers, it was 1:2 by weight, respectively) led to a rapid increase in the rolling down angle index in all cases. It can be assumed that this effect was due to formation of a dense packing of filler particles on the surface of the coating which was achieved by using bifractional systems [12]. Under these conditions, the fraction of fine particles occupies a free volume of the coarse-particle fraction packing thus ensuring a more dense location of the irregularities on the surface (Fig.…”

Section: Discussion Of the Relationship Between The Structure Of Hiermentioning

confidence: 99%

Study of structure influence on wear resistance of hierarchial superhydrophobic coatings

Myronyuk

Dudko

Baklan

et al. 2017

EEJET

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Coupled spreading-fraction effects of polymer nano-binder on the network connectivity and tensile modulus of porous mineral coatings

Alam

Toivakka

2012

Materials Letters

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Porous Particle-Polymer Composites

Cited by 3 publications

References 86 publications

Modulation of neuronal cell affinity of composite scaffolds based on polyhydroxyalkanoates and bioactive glasses

Modulation of neuronal cell affinity of composite scaffolds based on polyhydroxyalkanoates and bioactive glasses

Study of structure influence on wear resistance of hierarchial superhydrophobic coatings

Coupled spreading-fraction effects of polymer nano-binder on the network connectivity and tensile modulus of porous mineral coatings

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