Portable Raman spectroscopy applied to the study of drugs of abuse

Santos, Layla P.; Nascimento, Márcia H.C.; Barros, Iago H.A.S.; Santos, Nayara A. dos; Lacerda, Valdemar; Filgueiras, Paulo R.; Romão, Wanderson

doi:10.1111/1556-4029.15011

Cited by 8 publications

(2 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unsupervised mathematical methods to automate the identification of mixture components using reference spectral libraries have been reported [80–83]. Most of the handheld FT‐IR spectrometers shown in Figure 4 include an unsupervised, automated mixture analysis function based on spectral library searching.…”

Section: Vibrational Spectroscopymentioning

confidence: 99%

See 1 more Smart Citation

Field‐portable detection of fentanyl and its analogs: A review

Crocombe,

Giuntini,

Schiering

et al. 2023

Journal of Forensic Sciences

View full text Add to dashboard Cite

The need to detect fentanyl and its analogs in the field is an important capability to help prevent unintentional exposure or overdose on these substances, which may result in death. Many portable methods historically used in the field by first responders and other field users to detect and identify other chemical substances, such as hazardous materials, have been applied to the detection and identification of these synthetic opioids. This paper describes field portable spectroscopic methods used for the detection and identification of fentanyl and its analogs. The methods described are automated colorimetric tests including lateral flow assays; vibrational spectroscopy (mid‐infrared and Raman); gas chromatography–mass spectrometry; ion mobility spectrometry, and high‐pressure mass spectrometry. In each case the background and key details of these technologies are outlined, followed by a discussion of the application of the technology in the field. Attention is paid to the analysis of complex mixtures and limits of detection, including the required spectral databases and algorithms used to interrogate these types of samples. There is also an emphasis on providing actionable information to the (likely) non‐scientist operators of these instruments in the field.

show abstract

Section: Vibrational Spectroscopymentioning

confidence: 99%

“…have been reported[80][81][82][83]. Most of the handheld FT-IR spectrometers shown in Figure4include an unsupervised, automated mixture analysis function based on spectral library searching.…”

mentioning

confidence: 99%