Portal-drained viscera heat production in Iberian pigs fed betaine- and conjugated linoleic acid-supplemented diets

Rojas-Cano, M. L.; Lachica, M.; Lara, L.; Haro, A.; Fernández‐Fígares, I.

doi:10.1002/jsfa.7788

Cited by 4 publications

(3 citation statements)

References 52 publications

(131 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reduced size of the meal (<15 g/kg BW) of very low CP content (52 g/kg DM) offered could partially explain the lower PPF since a relationship between feed intake and blood flow has been reported ( Lomax & Baird, 1983 ; Huntington, 1984 ). In Iberian pigs we obtained differences in postprandial PBF related to the amount of feed intake; it was much lower when pigs were fed 0.25 ( González-Valero et al, 2016b ) than when they were offered the full daily ration ( Rojas-Cano et al, 2017 ).…”

Section: Discussionmentioning

confidence: 91%

Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites

Fernández‐Fígares

Rodríguez-López

González-Valero

et al. 2018

PeerJ

Self Cite

View full text Add to dashboard Cite

Most valuable cured products from Iberian pigs come from pure bred animals raised for a final grazing-fattening period where pigs eat mainly acorns, a low protein energy rich fruit. This is a nutritional challenge for animals fed equilibrated diets from weaning. The aim of the study was to determine net portal appearance (NPA) of metabolites in gilts fed acorns and evaluate adaptational changes after one week of feeding. Two sampling periods were carried out (after one day and after one week of acorn feeding) with six gilts (34 kg average BW) set up with three catheters: in carotid artery and portal vein for blood sampling, and ileal vein for para-aminohippuric acid (PAH) infusion to measure portal plasma flow (PPF). Pigs were fed at 2.5 × ME for maintenance a standard diet in two portions, at 09:00 (0.25) and 15:00 h (the remaining 0.75). On the day prior to the first sampling period, pigs were fed 2.4 kg of oak acorns. After feeding 0.25 of ration a 6 h serial blood collection was initiated. Following an identical protocol, a second sampling session was performed 1 week later. Adaptation to acorn consumption decreased NPA of ammonia (47%, P < 0.001). Although there was a transfer of urea from the gastrointestinal tract to the circulation in both sampling periods, no differences in NPA of urea was found (P > 0.05). NPA of glucose was not influenced by sampling period (P > 0.05), but NPA of lactate was greatly increased (231%, P < 0.001). There was a negative NPA of albumin although adaptation to acorn feeding did not alter it. Although NPA of triglycerides and cholesterol were unchanged, a subtle increase in arterial and portal cholesterol was noticed (9.6%, P < 0.01). Pigs fed a protein deficient diet for one week adapted decreasing NPA of ammonia for saving metabolic energy as less ammonia would become available for conversion to urea.

show abstract

Section: Discussionmentioning

confidence: 91%

Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites

Fernández‐Fígares

Rodríguez-López

González-Valero

et al. 2018

PeerJ

Self Cite

View full text Add to dashboard Cite

show abstract

“…There is not a clear explanation for the effect of betaine and CLA on PPF. Fasting intestinal blood flow is regulated by oxygen demand for oxidative metabolism (Gallavan and Chou, 1985), which is in line with the reduced PDV heat production in young Iberian pigs fed betaine or CLA diets (Rojas-Cano et al, 2017).…”

Section: Discussionmentioning

confidence: 78%

Net portal appearance of proteinogenic amino acids in Iberian pigs fed betaine and conjugated linoleic acid supplemented diets

Lachica

Rojas-Cano

Lara

et al. 2021

Animal Feed Science and Technology

View full text Add to dashboard Cite

“…For example, serum triacylglycerol was increased in Iberian pigs fed with CLA and betaine þ CLA supplemented diets. Betaine and CLA decreased portal-drained viscera heat production in Iberian pigs, increasing energy availability for other tissues, although the effects on growth performance depend on the energy available for growth and how it is partitioned between protein and fat (Rojas-Cano et al, 2017). Leptin, a polypeptide hormone secreted primarily by adipose tissue, appears to play a major role in feed intake and energy metabolism (Friedman and Halaas, 1998), and it has direct autocrine or paracrine effects on adipocytes (Fruhbeck et al, 1997), which in turn may contribute to the fat-reducing effect of leptin at the central nervous system level.…”

Section: Introductionmentioning

confidence: 95%

Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants

Fernández‐Fígares

Lachica

M³

et al. 2019

Animal

View full text Add to dashboard Cite

Consumers’ demand of leaner meat products is a challenge. Although betaine and conjugated linoleic acid (CLA) have the potential to decrease porcine adipose tissue, their mode of action is poorly understood. The aim of the study was to determine the lipolytic effect of betaine and CLA in the adipose tissue of Iberian pigs. Adipose tissue explants from five pigs (38 kg BW) were prepared from dorsal subcutaneous adipose tissue samples and cultivated for 2 h (acute experiments) or 72 h (chronic experiments). Treatments included 100 µM linoleic acid (control), 100 µM trans-10, cis-12 CLA, 100 µM linoleic acid + 1 mM betaine and 100 µM trans-10, cis-12 CLA + 1 mM betaine (CLABET). To examine the ability of betaine or CLA to inhibit insulin’s suppression of isoproterenol-stimulated lipolysis, test medium was amended with 1 µM isoproterenol ±10 nM insulin. Media glycerol was measured at the end of the incubations. Acute lipolysis (2 h) was increased by CLA and CLABET (85% to 121%; P < 0.05) under basal conditions. When lipolysis was stimulated with isoproterenol (1090%), acute exposure to betaine tended to increase (13%; P = 0.071), while CLA and CLABET increased (14% to 18%; P < 0.05) isoproterenol-stimulated lipolysis compared with control. When insulin was added to isoproterenol-stimulated explants, lipolytic rate was decreased by 50% (P < 0.001). However, supplementation of betaine to the insulin + isoproterenol-containing medium tended to increase (P = 0.07), while CLABET increased (45%; P < 0.05) lipolysis, partly counteracting insulin inhibition. When culture was extended for 72 h, CLA decreased lipolysis under basal conditions (18%; P < 0.05) with no effect of betaine and CLABET (P > 0.10). When lipolysis was stimulated by isoproterenol (125% increase in rate compared with basal), CLA and CLABET decreased glycerol release (27%; P < 0.001) compared with control (isoproterenol alone). When insulin was added to isoproterenol-stimulated explants, isoproterenol stimulation of lipolysis was completely blunted and neither betaine nor CLA altered the inhibitory effect of insulin on lipolysis. Isoproterenol, and especially isoproterenol + insulin, stimulated leptin secretion compared with basal conditions (68% and 464%, respectively; P < 0.001), with no effect of CLA or betaine (P > 0.10). CLA decreased leptin release (25%; P < 0.001) when insulin was present in the media, partially inhibiting insulin stimulation of leptin release. In conclusion, betaine and CLA produced a biphasic response regarding lipolysis so that glycerol release was increased in acute conditions, while CLA decreased glycerol release and betaine had no effect in chronic conditions. Furthermore, CLA and CLABET indirectly increased lipolysis by reducing insulin-mediated inhibition of lipolysis during acute conditions.

show abstract

Portal-drained viscera heat production in Iberian pigs fed betaine- and conjugated linoleic acid-supplemented diets

Cited by 4 publications

References 52 publications

Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites

Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites

Net portal appearance of proteinogenic amino acids in Iberian pigs fed betaine and conjugated linoleic acid supplemented diets

Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants

Contact Info

Product

Resources

About