Portal vein pressure and graft oxygen consumption monitoring during liver transplantation

Near‐infrared spectroscopy might be a useful tool for predicting the risk of vascular complications after pediatric liver transplants: Two case reports

“…In a porcine partial liver graft model, high intraoperative oxygen consumption was found to be related to lower hepatic artery flow, graft failure, and poor survival . In addition, increases in liver graft oxygen consumption and portal vein pressure are associated with greater portal vein resistance during adult liver transplantation . Acute graft rejection is associated with decreased hepatic blood flow and increased hepatic oxygen consumption .…”

Glucose Balance of Porcine Liver Allograft is an Important Predictor of Outcome

“…In liver transplantation complicated by primary non-function, portal vein or hepatic artery thrombosis, or hepatic vein obstruction prehepatic and posthepatic oxygen content difference at 100 min after reperfusion (3.2 6 0.8 volume %) was greater than those in successful transplant patients (1.7 6 0.8 volume %) [37]. In this study, greater oxygen consumption of the partial liver graft was also positively associated with negative glucose balance of the partial graft after reperfusion, and poor outcome and prognosis.…”

“…The normal liver consumes about 20%-25% of the whole body oxygen consumption [37,38], and higher rates of oxygen consumption of the liver graft in recipients of cadaveric whole liver grafts was associated with a poor prognosis [37]. In liver transplantation complicated by primary non-function, portal vein or hepatic artery thrombosis, or hepatic vein obstruction prehepatic and posthepatic oxygen content difference at 100 min after reperfusion (3.2 6 0.8 volume %) was greater than those in successful transplant patients (1.7 6 0.8 volume %) [37].…”

Understanding the splenic contribution to portal flow: The role of splenic artery ligation as inflow modification in living donor liver transplantation

“…Yagi et al23 reports a PVP >20 mm Hg being associated with poor graft outcome. Increased PVP is also associated with poor outcomes in recipients of whole liver grafts 24. The Kyoto group demonstrated a significantly poorer 6‐month patient survival in recipients of ALDLT grafts with PVP >20 mm Hg early in the first week after transplantation, compared with patients with PVP <20 mm Hg at the same time after transplantation 25.…”