Portal Vein Thrombosis in Patients with Cirrhosis: Outcome of Anticoagulation

Cheruvathur, Paul; Peter, George; Mashhood, V.; Vinayakumar, Krn; Sunil, Premaletha

doi:10.1016/j.jceh.2015.07.219

Cited by 1 publication

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“…Main characteristics of studies are summarized in Table 1. The sample size ranged from 16 [14,[20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] and 14 as abstracts [38][39][40][41][42][43][44][45][46][47][48][49][50][51].…”

Section: Included Studiesmentioning

confidence: 99%

Anticoagulation Favors Thrombus Recanalization and Survival in Patients With Liver Cirrhosis and Portal Vein Thrombosis: Results of a Meta-Analysis

Wang

Guo

et al. 2020

Adv Ther

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Introduction: Benefit and risk of anticoagulation in cirrhotic patients with portal vein thrombosis (PVT) remain controversial, especially in those with asymptomatic PVT and in non-liver transplant candidates. Furthermore, the predictors of portal vein recanalization and bleeding events after anticoagulation are critical for making clinical decisions, but still unclear. We conducted a meta-analysis to investigate the outcomes of anticoagulation for PVT in liver cirrhosis and explore the predictors of portal vein recanalization and bleeding events after anticoagulation. Methods: All studies regarding anticoagulation for PVT in liver cirrhosis were searched via PubMed, EMBASE, and Cochrane Library databases. Thrombotic outcomes, bleeding events, and survival were compared between anticoagulation and non-anticoagulation groups. Predictors of portal vein recanalization and bleeding events were pooled. Risk ratios (RRs) or mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Results: Thirty-three studies including 1696 cirrhotic patients with PVT were included. Anticoagulation significantly increased portal Electronic supplementary material The online version of this article (

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