“…Hyperspectral images, known as hypercubes, contain rich information on a wide range of spectra with a high spectral resolution [7], hence, dimensionality reduction, image processing, and machine learning techniques are applied to extract the useful information from the vast amounts of HSI data, and have made many of the advancements in cancer identification: (1) Dimensionality reduction techniques. The principal component analysis [8,9], tensor decompositions [10], and T-distributed stochastic neighbor approach [11,12], were to reduce the dimensionality of features in hyperspectral images for compact expression; (2) Image processing techniques. Fourier coefficients [13], normalized difference nuclear index [14], sparse representation [15], box-plot and the watershed method [16], superpixel method [9], markov random fields [17,18], and morphological method [19], were used for hyperspectral image processing and quantification analysis; (3) Machine learning techniques.…”