Position of simultaneous kidney and pancreas transplantation in treatment of diabetes accompanied with end-stage renal failure: case discussion and new approaches

Abstract

Type 1 diabetes, characterized with the loss of pancreatic islet cells and advanced with microvascular and macrovascular complications, is an autoimmune disease that can cause end stage renal failure. These patients have a chance to survive with hemodialysis and insulin therapy, but they may suffer from many co-morbidities and low quality of life. In this group of patients, simultaneous pancreas kidney transplantation is the only treatment modality that improves the quality and duration of life, providing normo-glycemic blood levels and dialysis-free life span. In this paper, we reviewed a simultaneous pancreas kidney transplanted case, the operation technique, treatment outcomes, and new trends.