Position of the Oxygen Dissociation Curve in Newborns with Transitory Hyperbilirubinaemia

Abstract

In newborns, suffering from transitory hyperbilirubinaemia, oxygen partial pressure of blood was measured at 50% oxygen saturation (p50). The p50 shows a decline with rising serum bilirubin on the 98-percent confidence level. The statistic values were 20.7 mm Hg at 0 and 19.6 mm Hg at 10 mg bilirubin/100 ml serum. The consequences for the icteric child are discussed.

Position of the Oxygen Dissociation Curve in Newborns with ABO Constellation between Mother and Child

“…In figure 1 all results together with the regression line are shown. Addi tionally, the regression line obtained from 77 newborns suffering from transitory hyperbilirubinaemia is shown in the figure (8).…”

“…In an earlier study we could demonstrate in newborn children with transi tory hyperbilirubinaemia a shift to the left o f the oxygen dissociation curve (8). This was in relation to the degree o f hyperbilirubinaemia and was caused by a decrease o f the intraerythrocyte 2,3-diphosphoglycerate level (7).…”