Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial

Peerbooms, Joost C; Sluimer, Jordi; Gosens, Taco

doi:10.1177/0363546509355445

Cited by 678 publications

(640 citation statements)

References 23 publications

Supporting

Mentioning

586

Contrasting

Unclassified

Order By: Relevance

“…These results correspond to data published by Peerbooms et al -a work comparing the results of treating patients with tendinopathy of the lateral epicondyle of the humerus with the use of PRP and steroid injections [6]. Considering that a reduction in the DASH point scores by at least 25 % was considered a success over the one year observation period, as many as 73 % of the treatments with PRP were successful compared to 49 % treated by steroid injections.…”

Section: Discussionsupporting

confidence: 89%

“…The literature proposes several options for treating lateral epicondylitis (LE), including activity modification, physical therapy, operative treatment, pharmacotherapy, of the injection of botulinum toxin, steroids, platelet rich plasma (PRP), autologous conditioned plasma (ACP) [2][3][4][5][6][7][8][9][10][11][12][13]. The origins of ACP and PRP usage were connected with dentistry and plastic surgery, and then later in Orthopedics and especially in sports medicine [14,15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

Purpose Chronic tendinopathy of lateral epicondyle of the humerus, commonly known as Btennis elbow^is one of the most frequent tendinopathies caused by recurrent overload of the muscle origins. The aim of the study was to assess the effectiveness of treating lateral epicondylitis (LE) with autologous conditioned plasma (ACP) and betamethasone injections, and to compare these methods over the course of a one year follow-up. Methods Patients were randomly placed into one of into two groups: 53 were treated with ACP, and 46 with 1 ml betamethasone injections and 2 ml of 1 % lignocaine. Both those groups were comparable in terms of initial DASH score. Results After six weeks and six months, the mean DASH score was significantly better in the betamethasone group, but was better in ACP group after one year. Full recovery (patients with no symptoms) at all time points was more common in the betamethasone group. A comparison of grouped DASH scores revealed more very good and good results in the ACP group after one year. More patients had pain symptoms related to injection in the ACP group than the betamethasone group. Conclusions ACP therapy of LE allows better results to be obtained at 12 months. Betamethasone injections give more rapid improvement, but the therapeutic effect is longer lasting in the ACP group.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…PRP use has hitherto been investigated in the treatment of lateral epicondylitis [6,7], knee osteoarthritis [8], hip osteoarthritis [9] patellar and Achilles tendinopathy [10][11][12], muscle injury [13] and anterior cruciate ligament injury [14]. Some studies concluded with promising outcomes that will hopefully set the new milestones of treatment options.…”

Section: Short Communicationmentioning

confidence: 99%

“…Some studies concluded with promising outcomes that will hopefully set the new milestones of treatment options. The effects of PRP treatment of lateral epicondylitis were compared with an autologous whole blood [6] and corticosteroid injections [7]: the analysis of 20 patients treated with PRP and 20 patients treated with whole blood for lateral epicondylitis showed that pain assessed by Visual Analog Scale (VAS), Mayo Elbow Performance Index, and pressure pain threshold (PPT) at 0, 4 and 8 weeks improved significantly in both populations. However, the authors indicated that 8 weeks after the treatment only the PRP group showed statistically significant improvement (P<0.05) [6].…”

Section: Short Communicationmentioning

confidence: 99%

“…However, the authors indicated that 8 weeks after the treatment only the PRP group showed statistically significant improvement (P<0.05) [6]. Another analysis of lateral epicondylitis treatment considered 51 patients treated with PRP and 49 patients treated with corticosteroid injections [7]. After 1 year, improvement was found in 73% of the PRP-treated patients and approximately 50 % of the corticosteroid-treated patients as regards VAS and Disabilities of the Arm, Shoulder and Hand (DASH) score for pain evaluation.…”

Section: Short Communicationmentioning

confidence: 99%

See 1 more Smart Citation

Extracellular Vesicles from Platelet-Rich Plasma as Conveyors of Regeneration Potential in Orthopedics

2014

J Hematol Thrombo Dis

View full text Add to dashboard Cite

A Review of the Evaluation, Treatment, and Rating of Lateral Epicondylitis

Arnett

Mandel

Aydin

et al. 2016

AMA Guides® Newsletter

View full text Add to dashboard Cite

Lateral epicondylitis, often called “tennis elbow,” is a musculoskeletal condition characterized by pain around the lateral elbow and adjacent forearm with resisted wrist extension or passive terminal wrist flexion with the elbow in full extension, plus tenderness over and/or just distal to the lateral epicondyle. The name is a misnomer because the pathology is neither inflammatory nor located in the lateral epicondyle but rather represents a chronic tendinosis with disorganized tissue and neovessels of the tendon originating from the extensor carpi radialis brevis muscle and less commonly the extensor digitorum communis muscle, which originate on the lateral epicondyle. Clinical assessment involves understanding the chronology, precipitating activities, current symptoms, and interference with activities of daily living. Physical examination is performed bilaterally and includes palpitation provocative testing, measuring elbow and wrist motions, and neurological evaluation. Many treatments have been proposed, but little quality evidence supports any specific approach; more than 90% of cases are managed nonoperatively. Severe cases that have failed at least months of nonoperative management may warrant surgical assessment, but studies of surgical results for treatment of lateral epicondylitis are limited. Impairment rating may be necessary in a minority of cases and involves using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Sixth Edition, based on diagnosis-based impairment and using Table 15-4, Elbow Regional Grid: Upper Extremity Impairments.

show abstract

Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial

Cited by 678 publications

References 23 publications

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Extracellular Vesicles from Platelet-Rich Plasma as Conveyors of Regeneration Potential in Orthopedics

A Review of the Evaluation, Treatment, and Rating of Lateral Epicondylitis

Contact Info

Product

Resources

About