Positive/Negative Symptomatology and Experimental Measures of Attention in Schizophrenic Patients

Hain, Christoph; Maier, Wolfgang; Klingler, Thomas; Franke, Petra

doi:10.1159/000284801

Cited by 29 publications

(26 citation statements)

References 16 publications

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“…Hence, the relationship between CPT performance and duration of illness/number of admissions (Table 2) indirectly confirms former results (Nuechterlein et al 1986, Strauss et al 1993, Hain et al 1993 suggesting relations between visual attention/information processing impairments and negative or deficit symptoms.…”

Section: Discussionsupporting

confidence: 82%

“…Strauss et al (1993) found no relationship between CPT and BPRS but confirmed the correlation between d' and thought disorder. Hain et al (1993) applied a CPT similar to that of the present study (CPT-M) to a sample of N = 49 schizophrenic inpatents and found a significant correlation between sensitivity and the attentional impairment rating and the composite score of the SANS (Andreasen 1989). Although psychopathology in the present study was documented with a different method (PANSS), the results are in accordance with former findings: no relationship between CPT-d' and positive symptoms was observed, and the correlation with thought disorder reported by Nuechterlein et al (1986) and Strauss et al (1993) was confirmed by the correlation with the cognitive PANSS syndrome (see Table 2).…”

Section: Discussionmentioning

confidence: 99%

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Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test

Maß

Wolf

Wagner

et al. 2000

European Archives of Psychiatry and Clinical Neurosciences

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The Continuous Performance Test (CPT) is a widely used procedure for sustained attention/vigilance measurement. However, though the key index of vigilance impairment is the decrement of sensitivity over time during the test period, only few studies have examined whether schizophrenics show a larger drop in CPT performance than do healthy controls. 48 schizophrenic inpatients and 48 controls were investigated with the Munich CPT (480 visual stimuli, 25% target stimuli, one stimulus per second). Stimuli were degraded by randomly inverting 40%, 41%, 42%, or 43% of the pixels. Results were calculated separately for three consecutive trial sections. Additionally, PANSS ratings, medication, and other clinical data were documented. Schizophrenics show a vigilance decrement over time, controls show a vigilance increase. Differential vigilance changes were not related to the level of stimulus degradation. Schizophrenics performed worse than controls only at the lowest degradation level. While overall sensitivity correlated negatively with the dose of atypical neuroleptics and benzodiazepines, vigilance shifts over time correlated negatively with the dose of typical neuroleptics. Furthermore, sensitivity was related to the cognitive PANSS syndrome, number of admissions/duration of illness. Differential sensitivity decrements of schizophrenics and controls can be shown if suited CPT procedures are used. The need for basic research on experimental conditions of the CPT as well as examination of the relationship between sustained attention/vigilance decrements and clinical features of schizophrenia is suggested.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test

Maß

Wolf

Wagner

et al. 2000

European Archives of Psychiatry and Clinical Neurosciences

View full text Add to dashboard Cite

show abstract

“…Assuming that Tr-Int had less communication problems with Tr-Pat, demograpic variables (including a scale for German proficiency), PANSS (Positive and Negative Syndrome Scale [26]), HAM-D (Hamilton Depression Scale [27]) and GAFS (Global Assessment of Function- ing Scale, DSM-IV Axis V [28]) were completed by Tr-Int for all patients. Considering efforts to develop dimensions of the PANSS [29][30][31], the evaluation of the PANSS also included the psychopathological symdromes of schizophrenia [32]. The two research diagnoses as well as the clinical diagnosis, all three according to ICD-10, were then compared for agreement.…”

Section: Methodsmentioning

confidence: 99%

Schizophrenic Disorders among Turkish Migrants in Germany

Yagdiran¹,

Maß²,

Krausz³

2001

Psychopathology

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Several studies have implied cultural differences in the psychopathology of schizophrenia between migrants and natives. In a diagnostically strictly controlled study, including comparison of diagnosis with a Turkish-speaking psychiatrist, 74 patients of Turkish and 48 of German origin, all with a diagnosis of schizophrenic disorder, were compared using PANSS and HAM-D. The Turkish sample showed higher depression and hostile excitement, even in the subsample of those with paranoid schizophrenia, and no differences in positive, negative or cognitive symptoms. The similarities especially concerning core symptoms reflect evidence from cross-cultural studies on schizophrenia. In conclusion this study shows main differences in psychopathology between psychotic migrants and natives, as discussed in the literature, may be mainly due to diagnostic differences.

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“…In fünf Arbeiten wurde die Span-Leistung mit klinischen Störungsmerkmalen von schizophrenen Patienten in Beziehung gesetzt, die bis auf die Probanden von Hain et al (1993) neuroleptisch mediziert waren. Zur Erfassung der Symptomatik dienten die Brief Psychiatrie Rating Scale (BPRS -Overall u.…”

Section: Span 0/apprehensionunclassified

Störungen der frühen Informationsverarbeitung und der Vigilanz als Vulnerabilitätsmarker für Schizophrenie

Suslow

Arolt²

1996

Fortschr Neurol Psychiatr

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Disordered processes of scanning iconic memory and vigilance deficits are well-known phenomena in schizophrenics. The "Span of Apprehension" and the "Continuous Performance Test" are among the most important research techniques assessing these impairments and are considered possible neuropsychological vulnerability markers of schizophrenia. Numerous studies compared schizophrenics with psychiatric control groups on these tasks to determine the specificity of the performance deficits which represents a central criterion for vulnerability markers. The review of the empirical results suggests a non-specificity of the performance of schizophrenics on the "Span of Apprehension" and the degraded stimulus version of the Continuous Performance Test. These findings are critically discussed with reference to the technical and methodological characteristics of the studies. Furthermore, studies are presented which examined the relationship of vigilance performance on the Continuous Performance Test and rate of detecting on "Span of Apprehension" and psychopathological symptoms with the aim to evaluate the marker qualities of these research techniques for schizophrenic symptoms. According to the available data a partial symptomatic specificity can be attributed to the "Span of Apprehension".

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Positive/Negative Symptomatology and Experimental Measures of Attention in Schizophrenic Patients

Cited by 29 publications

References 16 publications

Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test

Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test

Schizophrenic Disorders among Turkish Migrants in Germany

Störungen der frühen Informationsverarbeitung und der Vigilanz als Vulnerabilitätsmarker für Schizophrenie

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