Positron emission tomography of lung tumors and mediastinal lymph nodes using [18F]fluorodeoxyglucose

Scott, Walter J.; Schwabe, Jane L.; Gupta, Naresh; Dewan, Naresh A.; Reeb, Steve D; Sugimoto, Jeffrey T.

doi:10.1016/0003-4975(94)90730-7

Cited by 162 publications

(55 citation statements)

References 10 publications

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“…Considerable experience is now available regarding the diagnostic value of FDG PET in solitary pulmonary nodules. Table 1 summarizes the main reported studies, including the date of publication, the number of patients studied, and sensitivity and specificity [70,92,[98][99][100][101][102][103][104][105][106][107]. As can be seen, a high sensitivity has been achieved by all groups (average 96%).…”

Section: Results In Selected Organs and Cancer Typesmentioning

confidence: 99%

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Rigo¹,

Paulus²,

et al. 1996

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Abstract. Positron emission tomography (PET) is now primarily used in oncological indication owing to the successful application of fluorine-18 fluorodeoxyglucose (FDG) in an increasing number of clinical indications at different stages of diagnosis, and for staging and followup. This review first considers the biological characteristics of FDG and then discusses methodological considerations regarding its use. Clinical indications are considered, and the results achieved in respect of various organs and tumour types are reviewed in depth. The review concludes with a brief consideration of the ways in which clinical PET might be improved.

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Section: Results In Selected Organs and Cancer Typesmentioning

confidence: 99%

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Rigo¹,

Paulus²,

et al. 1996

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“…False-positive PET findings in the lung are seen in tuberculous infection, histoplasmosis and rheumatoid lung disease. False negatives are seen with carcinoid tumours, bronchoalveolar carcinoma and lesions v10 mm in size [58][59][60][61].…”

Section: Positron Emission Tomographymentioning

confidence: 99%

“…PET scanning detects malignancy in focal pulmonary opacities with a sensitivity of 96%, specificity of 88% and an accuracy of 94% in lesions of o10 mm [53][54][55][56][57][58]. However, compared to CT, PET has poorer spatial resolution, which precludes it from accurate anatomical assessment of primary tumour status [59].…”

Section: Positron Emission Tomographymentioning

confidence: 99%

Diagnostic imaging of lung cancer

Hollings¹,

Shaw²

2002

Eur Respir J

124

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Carcinoma of the bronchus is the most common malignancy in the Western world. It is also the leading cause of cancer-related death accounting for 32% of all cancer deaths in males and 25% in females [1]. In the USA it causes more deaths than cancers of the colon, breast and prostate combined [2]. Disappointingly, in a recent UK survey of improvements in cancer survival [3], carcinoma of the bronchus showed the smallest percentage reduction in the number of deaths avoided between 1981-1990 (0.2%). This compares badly with breast (11% reduction) and melanoma (32%). The overall 5-yr survival for lung cancer diagnosed between 1986-1990 was only 5.3% (against 66% for breast and 76% for melanoma). It is on this background that the radiologist remains actively employed in the detection, diagnosis, staging and review of this common malignancy.

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“…Endobronchial ultrasonography (EBUS) has been used for imaging guidance for TBB of PPLs [6,7]. Furthermore, Kurimoto et al and our own preliminary study have shown the feasibility and effectiveness of TBB using EBUS with a guide sheath (EBUS-GS) [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions

Mizugaki¹,

Shinagawa²,

Kanegae³

et al. 2010

Lung Cancer

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SummaryTo evaluate the combination of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS) and positron emission tomography with fluorodeoxyglucose (FDG-PET) for the diagnosis of small peripheral pulmonary lesions (PPLs) ≤30 mm in mean diameter. A total of 74 PPLs (69.2%) were diagnosed by TBB using EBUS-GS with X-ray fluoroscopy. Diagnostic yield by FDG-PET was 78.5% for the 107 PPLs examined. Diagnostic yield with the combination of TBB using EBUS-GS and FDG-PET (90.7%) was significantly higher compared with that for each procedure alone. A significant increment in diagnostic yield with this combination was seen for PPLs >20 mm and ≤30 mm and for malignant lesions. Combination of TBB using EBUS-GS and FDG-PET is useful for the diagnosis of small PPLs.-3 -

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Positron emission tomography of lung tumors and mediastinal lymph nodes using [18F]fluorodeoxyglucose

Cited by 162 publications

References 10 publications

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Diagnostic imaging of lung cancer

Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions

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