Possibilities of Application of Low- Temperature Air Pressure in the Treatment of Burn Wounds

Zinoviev, E. V.; Tsygan, V. N.; Asadulaev, Marat S.; Borisov, Oleg V.; Lopatin, Ivan; Luk'ianov, S A; Artsimovich, I.V.; Paneiakh, Moisei B.; Kostiakov, Denis; Кравцов, С А; Osmanov, K. F.

doi:10.1615/plasmamed.2018028250

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…CAPP have also been used to effectively treat burns in 44 Wistar Kyoto rats with 11 rats untreated, 11 rats treated with CAPP, 11 rats treated with antiseptic, and 11 rats treated with levomecol [57]. Treating wounds with CAPP leads to final healing after 18 days, compared to 24 days with levomecol, 28 days with antiseptics, and 35 days with no treatment.…”

Section: Burn Wound Treatmentmentioning

confidence: 99%

A Review of Cold Atmospheric Pressure Plasmas for Trauma and Acute Care

Garner¹,

Mehlhorn²

2021

Front. Phys.

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Despite the high overall survival rates of severely injured military and civilian personnel requiring trauma and acute care, the challenges of treating infections and healing-resistant wounds have grown. Exposure to unknown environmental pathogens at the wound, including parasites and antibiotic resistant microorganisms, hinders timely and effective treatment using traditional techniques. Cold atmospheric pressure plasma (CAPP) provides a promising biophysical tool to address these issues by applying physically created modalities that cannot be circumvented by bioresistance to inactivate microorganisms and enhance wound healing. CAPPs generate charged particles and numerous reactive oxygen species (ROS) and reactive nitrogen species (RNS) that act on biological cells and tissues, often through plasma membrane interactions. This review fills a gap in the plasma medicine literature by specifically focusing on applying CAPPs for acute trauma, such as surgery, wound treatment, and disinfection. After briefly highlighting the areas of opportunity for improving acute trauma treatment and the fundamentals of CAPP generation, this review details emerging applications of CAPPs for enhanced wound healing, burn treatment, transdermal delivery, and surgical applications. We also discuss CAPP optimization through novel device design and synergistic combination with traditional treatment technologies to transition this biophysical technology to the battlefield and acute care settings.

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Section: Burn Wound Treatmentmentioning

confidence: 99%

A Review of Cold Atmospheric Pressure Plasmas for Trauma and Acute Care

Garner¹,

Mehlhorn²

2021

Front. Phys.

View full text Add to dashboard Cite

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Surface Properties of Fluorocarbon Coatings Produced by Low-Frequency Plasmatron at Atmospheric Pressure

2023

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This paper presents the results of studies conducted on coatings based on thin fluorocarbon films obtained by plasma-enhanced chemical vapor deposition using low-frequency plasmatron and low-temperature plasma at atmospheric pressure. The possibility of forming thin fluorocarbon layers by supplying a cyclohexane/carbon tetrafluoride gas mixture to substrates made of polymeric materials (polyethylene terephthalate and polystyrene) has been demonstrated and the main technological modes of deposition process have been established. The absorption spectra of the obtained coatings were studied, the influence of the gas discharge energy contribution on the concentration of fluorocarbon compounds was established, and the band gap was calculated using the Tauc method. The surface relief of the obtained structures was considered using atomic force microscopy and the root-mean-square deviation of the surface roughness was calculated, which reached a maximum of 36 ± 3 nm. Using the Oliver-Pharr method, the nanohardness and Young's modulus of elasticity of the obtained coatings were calculated, which amounted to 0.447 ± 0.025 and 6.10 ± 0.39 GPa, respectively.

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Possibilities of Application of Low- Temperature Air Pressure in the Treatment of Burn Wounds

Abstract: of low-temperature air plasma of an atmospheric pressure arc discharge for treatment of thirddegree skin burns in laboratory rats. Thermal skin burns were produced by our own original p < 0.05) p < 0.01).

Cited by 2 publications

References 6 publications

A Review of Cold Atmospheric Pressure Plasmas for Trauma and Acute Care

A Review of Cold Atmospheric Pressure Plasmas for Trauma and Acute Care

Surface Properties of Fluorocarbon Coatings Produced by Low-Frequency Plasmatron at Atmospheric Pressure

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