Possibilities of phytotherapy in patients with lower urinary tract symptoms due to benign prostate enlargement

Al-Shukri, Adel Salmanovich; Сальманович, Аль-Шукри Адель; Kostyukov, Stanislav V.

doi:10.17816/uroved48969

Cited by 3 publications

(1 citation statement)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Одно из направлений консервативной терапиифитотерапия, к особенностям которой относится хорошая переносимость: побочные эффекты лечения редки и обычно слабо выражены [10]. Во многих странах мира пациенты с СНМП отдают предпочтение именно препаратам растительного происхождения.…”

Section: оригинальные статьиunclassified

Efficacy evaluation of entomological drug Adenoprosin® usage in combined treatment of patients with lower urinary tract symptoms due to benign prostate enlargement

Al-Shukri

Kostyukov

Maksimova

2021

Urology reports (St. - Petersburg)

Self Cite

View full text Add to dashboard Cite

BACKGROUND: Increasing the effectiveness of treatment of patients with symptoms of the lower urinary tract is one of the main problems of modern urology, which is associated both with their high prevalence and with a significant deterioration in the quality of life of patients. AIM: The article presents the results of the usage of the entomological drug Adenoprosin in the combined treatment of patients with lower urinary tract symptoms due to benign prostatic enlargement. MATERIALS AND METHODS: 80 patients were treated (mean age 63.6 6.4 years). At the initial phase of the study, all patients received Tamsulosin 0.4 mg once a day for 4 weeks. At the second phase, the patients were divided into two groups. Group 1 patients were prescribed a combination therapy with Adenoprosin (1 rectal suppository (150 mg) at night, for a course of 30 suppositories) and Tamsulosin (0.4 mg per day). Patients of the 2nd group continued monotherapy with Tamsulosin (0.4 mg per day). The duration of the second phase of treatment was 4 weeks. RESULTS: The results of the study showed a more pronounced positive dynamics of clinical indicators in patients of the 1st group, who received combination therapy with Adenoprosin and Tamsulosin, compared to patients of the 2nd group. There was a more pronounced decrease in the IPSS score, an improvement in the quality of life, an increase in the urine flow rate and a decrease in the volume of residual urine. The volume of the prostate gland did not change significantly. When examined 2 weeks after the end of treatment, the positive dynamics of clinical indicators in patients of the 1st group persisted. The tolerability of the treatment was satisfactory in patients of both groups. CONCLUSIONS: The results of the study indicate the advisability of including Adenoprosin in the combination therapy of patients with lower urinary tract symptoms due to benign enlargement of the prostate gland.

show abstract

Section: оригинальные статьиunclassified

Efficacy evaluation of entomological drug Adenoprosin® usage in combined treatment of patients with lower urinary tract symptoms due to benign prostate enlargement

Al-Shukri

Kostyukov

Maksimova

2021

Urology reports (St. - Petersburg)

Self Cite

View full text Add to dashboard Cite

show abstract

Prostate diseases: pathogenetic bases and therapeutic possibilities of entomotherapy

Kuzmin

Slesarevskaya

2022

Androl. genit. hir.

View full text Add to dashboard Cite

The review article is devoted to the history of creation, biological effects and clinical application of the entomological drug Adenoprosin. The data of experimental studies are presented, indicating a high biological activity of the drug, the mechanisms of its therapeutic action are described. The pharmacological effects of Adenoprosin were analyzed, which ensure its high clinical efficacy and good tolerability. The pathogenetic validity of the appointment of Adenoprosin in patients with chronic prostatitis and benign prostatic hyperplasia was shown.

show abstract

Assessment of copulative function and severity of lower urinary tract symptoms in patients with benign prostatic hyperplasia after transurethral enucleation

Vydrin

Kalinina

Burlaka

et al. 2021

Urology reports (St. - Petersburg)

View full text Add to dashboard Cite

AIM: was to conduct a comparative assessment of copulative function and the severity of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH) who underwent laser and bipolar transurethral enucleation of the prostate and who treated conservatively. MATERIALS AND METHODS: 143 BPH patients aged 50 to 80 years (mean age 65 years) with complaints of copulatory and urinary disorders were under observation. All patients were divided into two groups. The 1st (main) group included 102 patients who underwent surgical treatment: transurethral laser enucleation of the prostate (n = 55) and transurethral bipolar enucleation of the prostate (n = 47). Patients of the 2nd group (n = 41) received conservative treatment. Control examinations were performed before treatment, 4, 12 and 24 weeks after it. RESULTS: All 102 patients of group 1, regardless of the type of surgery, noted retrograde ejaculation four weeks after surgery. In the majority of patients of the 1st group during these periods weakening of orgasm was noted, in a significant number deterioration of erection and decreased libido were noted. Upon further observation, by the 12th week after the operation, restoration of all components of the copulatory function was noted, with the exception of ejaculation. By the 24th week of observation, only in 2 patients of the 1st group the normal mechanism of ejaculation was restored. Surgical treatment of patients in group 1, regardless of the method of surgery, led to a significant decrease in the severity of LUTS, an increase in the maximum urine flow rate, a decrease in the volume of the prostate gland and the amount of residual urine. There were no significant differences in the dynamics of these indicators depending on the method of transurethral enucleation. The patients of the 2nd group also had an improvement in clinical parameters, but it was much less pronounced than in the 1st group. CONCLUSION: Laser and bipolar transurethral enucleation of the prostate are effective surgical techniques that significantly improve the outflow of urine from the bladder, reduce the severity of LUTS and improve the sexual function of patients. Surgery is well tolerated by patients. At the same time, almost all patients operated on by these methods develop retrograde ejaculation.

show abstract

Possibilities of phytotherapy in patients with lower urinary tract symptoms due to benign prostate enlargement

Cited by 3 publications

References 6 publications

Efficacy evaluation of entomological drug Adenoprosin® usage in combined treatment of patients with lower urinary tract symptoms due to benign prostate enlargement

Efficacy evaluation of entomological drug Adenoprosin® usage in combined treatment of patients with lower urinary tract symptoms due to benign prostate enlargement

Prostate diseases: pathogenetic bases and therapeutic possibilities of entomotherapy

Assessment of copulative function and severity of lower urinary tract symptoms in patients with benign prostatic hyperplasia after transurethral enucleation

Contact Info

Product

Resources

About