Possibility for the Presence of Helicobacter pyloriin Drinking Well Water

Imanishi, Yasutsugu; Ogata, Tetsuya; Matsuzuka, Atsuko; Tasaki, Takako; Fujioka, Toshio; Akashi, Mitsunobu; Makino, Yoshihiro; Nishizono, Akira

doi:10.11150/kansenshogakuzasshi1970.77.18

Cited by 7 publications

(4 citation statements)

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“…In developing countries, water rather than person-to-person spread plays a significant role in the transmission of H. pylori (Akcam et al 2000). Water from streams, rivers and wells has been considered as a common source (Hulten et al 1991(Hulten et al , 1996Klein et al 1991;Mackay et al 1998;Hegarty et al 1999;Engstrand 2001;Mackay et al 2001;Mazari-Hiriart et al 2001;Lu et al 2002;Imanishi et al 2003;Karita et al 2003;Azevedo et al 2004;Gomes & De Martinis 2004;Rolle-Kampczyk et al 2004). In Brazil, Zaterka & colleagues (2007) confirmed that the source of drinking water in childhood was a risk factor for H. pylori infection and that the prevalence of H. pylori infection was higher when a local river was the source of drinking water and lower when this water was filtered or boiled.…”

Section: Transmission Of H Pylori In Watermentioning

confidence: 99%

Transmission of Helicobacter pylori and the role of water and biofilms

Percival

Thomas

2009

Journal of Water and Health

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Documented evidence relating to the survival of Helicobacter pylori outside the gastric niche is extremely limited. To date the primary transmission routes of H. pylori have yet to be confirmed and when this is achieved preventive infection control measures can be implemented to reduce and ultimately prevent human infection from this pathogen. There is mounting evidence which suggests that the prevalence of H. pylori infection has a strong correlation with access to clean water, suggesting a transmission route to the host. However, there are no established culture methods for the detection of viable H. pylori in the environment, in particular drinking water supplies, preventing the development of true epidemiological and risk assessments. The aim of this review is to highlight the available data to date that suggests drinking water and possible survival in biofilms as a probable transmission mode for H. pylori.

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Section: Transmission Of H Pylori In Watermentioning

confidence: 99%

Transmission of Helicobacter pylori and the role of water and biofilms

Percival

Thomas

2009

Journal of Water and Health

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“…Furthermore, the role of water sources and associated biofilms acting as environmental transmitters of H. pylori has been suggested by the detection of H. pylori DNA by PCR in sewage (Lu et al. 2002), well water (Imanishi et al. 2003), pond and river water (Horiuchi et al.…”

Section: Introductionmentioning

confidence: 99%

Detection of Helicobacter pylori by PCR but not culture in water and biofilm samples from drinking water distribution systems in England

Watson¹,

Owen²,

Said³

et al. 2004

J Appl Microbiol

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Aims: To investigate treated water distribution systems in England as a source of Helicobacter pylori. Methods and Results: Water and biofilms were obtained from 11 domestic and seven educational properties and from hydrants, reservoirs and water meters supplied by three water utilities. Samples were cultured on nonselective and antibiotic containing media combined with immunomagnetic separation concentration. Viable helicobacters were not detected in any of the 151 samples but Helicobacter-specific PCR assays detected DNA in 26% of samples from domestic properties, schools and hydrants with the highest frequency in biofilms (42%). Direct sequencing of six selected amplicons confirmed >95% sequence homology to H. pylori. Conclusions: While viable helicobacters were not isolated, evidence was obtained for the presence of Helicobacter DNA, including that of H. pylori. Biofilms on surfaces within water distribution systems may act either as sites for the passive accumulation of helicobacters or as potentially important reservoirs of infection. Significance and Impact of the Study: Our findings strengthen evidence that H. pylori may be transmitted through drinking water. However, there is currently no evidence that viable cells can survive the disinfection levels used in UK mains supplies and the health risk from this source remains unclear.

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“…Similarly, studies in Japan have reported higher infection rates in children who live in areas near the downstream parts of rivers than in those living in midstream areas [13]. Another study also detected the H. pylori gene by polymerase chain reaction in well water [7]. In our study, we investigated the relationship between H. pylori infection and the uses of well water and pit toilets during childhood.…”

Section: Discussion/conclusionmentioning

confidence: 78%

“…Helicobacter pylori infection has been considered a cause of various diseases, such as gastric cancer, gastric or duodenal ulcers, and mucosa-associated lymphoid tissue lymphoma [1][2][3][4]. Epidemiological studies have reported that H. pylori infection is influenced by the environment during childhood [5], and some reports have been published about oral infection among family members, particularly transmission from mothers to infants [6], or infection caused by ingesting well water [7], as well as other infection routes that remain unclear. This study conducted among young adults aimed to clarify the influence of lifestyle and the environment during childhood on the rate of H. pylori infection.…”

Section: Introductionmentioning

confidence: 99%

Influence of Living Environment during Childhood on Helicobacter pylori Infection in Japanese Young Adults

et al. 2019

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Introduction: Helicobacter pylori infection is usually established during childhood, for which certain responsible environmental factors have been identified. However, the details of the infection routes remain unclear. Objective: To determine the relation between H. pylori infection statuses and living environment of Japanese young adult. Methods: The subjects were 449 healthy young adult medical students of Tsukuba University (299 men and 150 women, mean age: 22.8 years). The H. pylori infection statuses were investigated using the rapid urease test or urine antibody. Questionnaires regarding sanitary conditions including usage of pit toilet or well water and experience of living with one's grandparents during childhood were surveyed. Each item was compared between the H. pylori-positive and-negative groups. Results: Among all participants, 33 (7.3%) were H. pylori-positive. The usage rates of pit toilets were 12.1 and 3.1% for the H. pylori-positive and-negative groups respectively (p = 0.03; OR 4.35, 95% CI 1.33-14.22). The usage rates of well water were 24.2 and 13.7% for the H. pylori-positive and-negative groups respectively (p = 0.07; OR 2.12, 95% CI 0.91-4.98). The proportion of participants with a history of living with their grandparents was significantly greater in the H. pylori-positive group (46.7%) than in the-negative group (20.9%; p = 0.03; OR 3.28, 95% CI 1.13-9.54). Only a history of living with one's grandparents during childhood showed statistical significance in the multivariate regression analysis (p = 0.04; OR 3.20, 95% CI 1.08-9.49). Conclusions: These results suggest that H. pylori infection is more strongly related to living with one's grandparents than living in a hygienic environment.

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Possibility for the Presence of Helicobacter pyloriin Drinking Well Water

Cited by 7 publications

References 0 publications

Transmission of Helicobacter pylori and the role of water and biofilms

Transmission of Helicobacter pylori and the role of water and biofilms

Detection of Helicobacter pylori by PCR but not culture in water and biofilm samples from drinking water distribution systems in England

Influence of Living Environment during Childhood on Helicobacter pylori Infection in Japanese Young Adults

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