Possible case scenarios and logistic issues in H5N1 pandemic

Tsang, Kenneth W.; Shim, Young Soo; Wong, Thomas; Liam, Chong Kin; Eng, Philip; Lam, Wai Yip; Seto, W. H.

doi:10.1111/j.1440-1843.2006.00885.x

Cited by 5 publications

(5 citation statements)

References 14 publications

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“…Extensive research on pharmacotherapy, largely basic and pre‐clinical at present, is underway. Efforts to prevent H5N1 infections in poultry could also be a key factor in preventing animal‐to‐human transmission of this highly fatal disease 66 …”

Section: H5n1 Avian Influenzamentioning

confidence: 99%

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Respiratory infections unique to Asia

Tsang

File

2008

Respirology

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Respiratory infections unique to AsiaTSANG KW, FILE TM Jr. Respirology 2008; 13: 937-949 Abstract: Asia is a highly heterogeneous region with vastly different cultures, social constitutions and populations affected by a wide spectrum of respiratory diseases caused by tropical pathogens. Asian patients with community-acquired pneumonia differ from their Western counterparts in microbiological aetiology, in particular the prominence of Gram-negative organisms, Mycobacterium tuberculosis, Burkholderia pseudomallei and Staphylococcus aureus. In addition, the differences in socioeconomic and health-care infrastructures limit the usefulness of Western management guidelines for pneumonia in Asia. The importance of emerging infectious diseases such as severe acute respiratory syndrome and avian influenza infection remain as close concerns for practising respirologists in Asia. Specific infections such as melioidosis, dengue haemorrhagic fever, scrub typhus, leptospirosis, salmonellosis, penicilliosis marneffei, malaria, amoebiasis, paragonimiasis, strongyloidiasis, gnathostomiasis, trinchinellosis, schistosomiasis and echinococcosis occur commonly in Asia and manifest with a prominent respiratory component. Pulmonary eosinophilia, endemic in parts of Asia, could occur with a wide range of tropical infections. Tropical eosinophilia is believed to be a hyper-sensitivity reaction to degenerating microfilariae trapped in the lungs.This article attempts to address the key respiratory issues in these respiratory infections unique to Asia and highlight the important diagnostic and management issues faced by practising respirologists.

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Section: H5n1 Avian Influenzamentioning

confidence: 99%

“…Efforts to prevent H5N1 infections in poultry could also be a key factor in preventing animal-to-human transmission of this highly fatal disease. 66…”

Section: H5n1 Avian Influenzamentioning

confidence: 99%

Respiratory infections unique to Asia

Tsang

File

2008

Respirology

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“…More than 200 human cases have occurred, with a cumulative case fatality of approximately 50%. Although the current strains of H5N1 are poorly transmissible from human to human, reassortment of genes may occur to allow enhanced infectivity as has happened with other influenza strains and a pandemic could ensue [6]. The World Health Organization has warned that a global pandemic may be at hand.…”

Section: The Threatmentioning

confidence: 99%

Facing the Next Pandemic: Ready or Not

Wingard

2007

Biology of Blood and Marrow Transplantation

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“…The different possible case scenarios and logistic issues relevant to an H5N1 pandemic are discussed in a guest editorial. 85 The worst case scenario is presented in which 10-20% of an entire population could become affected and become gravely ill requiring intensive care therapy and cross-infecting healthcare workers and other patients, and thus rapidly paralysing health-care systems. It is suggested that no contingency plan could cater for such health-care requirements and prioritization would be needed to preserve key personnel for the aftermath.…”

Section: Respiratory Infectionsmentioning

confidence: 99%