Possible Diabetic-Foot Complications in Sub-Saharan Africa

Agwu, Ezera; Dafiewhare, Ephraim O.; Ekanem, Peter E.

doi:10.5772/29227

Cited by 14 publications

(17 citation statements)

References 30 publications

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“…14 Diabetic foot problems account for more hospital admission than any other long term complications of diabetes and are responsible for nearly 50% of all-diabetes-related hospital bed days. 15 The lifetime risk of a patient with diabetes developing a DFU is 25%, and up to 85% of all lower-limb amputations in diabetes are preceded by foot ulcers. 13,16 Diabetic foot ulcer affects not only the quality of life and physiological welfare but also premortal events and following major leg amputations due to the ulcer, mortality ranges from 24.6% within 5 years and 45.4% within 10 years.…”

Section: Introductionmentioning

confidence: 99%

<p>Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study</p>

Adem¹,

Andargie²,

Teshale³

et al. 2020

DMSO

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The incidence of a diabetic foot ulcer (DFU) is increasing over the previous decade with an increasing prevalence of diabetes mellitus (DM). Despite the increasing incidence of DFU, there is limited information about the problem in Ethiopia. Hence, this study aimed to investigate the incidence of DFU and its predictors among newly diagnosed DM patients who were on follow-up at Felege Hiwot Referral Hospital. Methods: Institution-based retrospective follow-up study was conducted at Felege Hiwot Referral Hospital among newly diagnosed DM patients from January 1, 2009, to December 31, 2018. A simple random sampling method was used to select 401 study participants from a total of 723 eligible population. Data was entered using Epi-Data version 3.1 and exported to STATA version 14 for analysis. The incidence rate was estimated using person-years of observation and Nelson-Aalen cumulative hazard function, showing the cumulative probability of diabetic foot ulcer, was done. The best model (Gompertz) was selected using the AIC and log-likelihood method. Hazard ratio (HR) with its 95% confidence interval was computed and variables having a p-value less than 0.05 in the multivariable model were considered to be significantly associated with DFU. Results: A total of 387 patients were followed retrospectively for a median follow-up time of 95 months. Out of all, 66 (17.05%) patients developed DFU with an incidence rate of 4 cases per 100 person-years of observation. Diabetic nephropathy (adjusted hazard ratio (AHR) = 2.37, 95% CI: 1.33-54.24), diabetic retinopathy (AHR = 5.56, 95% CI: 2.64-11.74), and increased body mass index (AHR = 1.13, 95% CI: 1.01-1.27) were found to increase the hazard of DFU. Conclusion: The incidence of DFU was relatively high. Diabetic nephropathy, diabetic retinopathy, and body mass index were its significant predictors. Therefore, close monitoring of patients with co-morbidities and increased body mass index should be considered to reduce DFU.

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Section: Introductionmentioning

confidence: 99%

<p>Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study</p>

Adem¹,

Andargie²,

Teshale³

et al. 2020

DMSO

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“…In Sub-Saharan Africa, fast uncontrolled urbanization and changes in standard of living are responsible for the rising epidemic of DM and the observed increase presents a substantial public health and socioeconomic burden in the face of scarce resources [14]. The prevalence of undiagnosed diabetes mellitus is high in most countries of sub-Saharan Africa, and individuals who are unaware they have the disorder are at very high risk of chronic complications [15].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Factors Associated With Diabetic Foot Ulcer among Adult Patients in Ayder Referral Hospital Diabetic Clinic Mekelle, North Ethiopia, 2013

Solomon¹

2015

J Diabetes Metab

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Background: Diabetes mellitus is one of the most common metabolic disorders which is characterized by multiple long-term complications affecting almost every system in the body. Foot ulcer is one of the main complications of diabetes mellitus. The prevalence of foot ulcers ranges from 4% to 10% among persons diagnosed with diabetes mellitus. The objective of this study was to assess the prevalence factors associated with foot ulcer among diabetes patients in Ayder referral hospital. Methods: This institutional based cross sectional study was conducted in Ayder referral hospital from in December 2013-January 2014. Systematic random sampling was used to select 228 participants. Structured questionnaire developed from the literatures was used to collect data. Data analysis was done manually and summarized using descriptive statistics as well as texts, figures, and tables were used to present the findings. Data was collected after getting approval for the project proposal from Mekelle university department of nursing ethical review committee. Result: Among the 228 study participants all of them have regular follow up to the diabetic clinic of Ayder Referral hospital and 75% of them had type 2 diabetic mellitus. 12% of the 228 diabetic patients have foot ulcer currently with 38% of them are with Wagner's grade 0 Conclusion: this study concluded that 12% diabetic patients have foot ulcer. The main reasons to develop foot ulcer were poor glycemic control, wearing inappropriate Shoes and having no special foot care.

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“…6 It is estimated that 50% of diabetes related hospital admissions are due to DFU. 7 DFU can lead to infection, gangrene, amputation, and even death if necessary care is not provided. Overall, the rate of lower limb amputation in patients with DM is 15 times higher than patients without diabetes.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, it is reported that every 30 seconds one leg is amputated due to DFU worldwide. 7 A study from Tanzania in 1997–8 found that 33% of patients admitted with foot ulcers had amputations. The mortality rate was 29%.…”

Section: Introductionmentioning

confidence: 99%

The challenge of diabetic foot care: Review of the literature and experience at Queen Elizabeth Central Hospital in Blantyre, Malawi

Kasiya¹,

Mang’anda²,

Heyes³

et al. 2017

Mal. Med. J

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Possible Diabetic-Foot Complications in Sub-Saharan Africa

Cited by 14 publications

References 30 publications

<p>Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study</p>

<p>Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study</p>

Prevalence and Factors Associated With Diabetic Foot Ulcer among Adult Patients in Ayder Referral Hospital Diabetic Clinic Mekelle, North Ethiopia, 2013

The challenge of diabetic foot care: Review of the literature and experience at Queen Elizabeth Central Hospital in Blantyre, Malawi

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