Possible Interaction Between Sevoflurane and <i>Aloe vera</i>

Lee, Anna; Chui, Po Tong; Aun, C. S. T.; Gin, Tony; Lau, Angel S. C.

doi:10.1345/aph.1e098

Cited by 62 publications

(37 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[32] In 1 instance, a possible sevoflurane-Aloe vera interaction may be responsible for a women losing approximately 5 liters of blood during surgery. [51] …”

Section: Clinical Studies On the Effects Of Aloe Vera On Cancermentioning

confidence: 99%

Aloe Vera and Cancer

Ünlü¹

2016

TJ Oncol

View full text Add to dashboard Cite

SUMMARYAloe vera, a succulent plant species, has a long history in folk medicine. Its clear, viscous liquid has been used to treat skin problems and other disorders since ancient times. In the last century, oral consumption and the injection of aloe have also come to popular attention. Its topical use is effective in the treatment of burns and abrasions, and oral use is effective in the treatment of constipation. However, it has not been found to be superior to standard treatments. Most recently, claims of anti-cancer properties are prevalent. It has been found to inhibit proliferation and angiogenesis, and to induce apoptosis in cancer cells. Yet other clinical studies indicate that Aloe vera did not prevent or reduce the number of radiotherapy-related lesions; it merely delayed onset. Furthermore, many instances of toxicity and mortality have been reported in the literature. Today, it is better to avoid it, especially forms taken orally or by injection.

show abstract

“…[32] In 1 instance, a possible sevoflurane-Aloe vera interaction may be responsible for a women losing approximately 5 liters of blood during surgery. [51] …”

Section: Clinical Studies On the Effects Of Aloe Vera On Cancermentioning

confidence: 99%

Aloe Vera and Cancer

Ünlü¹

2016

TJ Oncol

View full text Add to dashboard Cite

show abstract

“…In conclusion,there is a potential herb-drug interaction between Aloe vera and sevoflurane based on the antiplatelet effects of these two agents. Lee A. group suggested that herbal medications with antiplatelet potential should be discontinued before anesthesia and surgery [19] . The biological vehicle effect will reduce the amount of test agent needed to produce the therapeutic response.…”

Section: Acemannan Propertiesmentioning

confidence: 99%

Immune Modulation of Aloe vera: Acemannan and Gut Microbiota Modulator

Yagi

Yu²

2015

Journal of Gastroenterology and Hepatology Research

View full text Add to dashboard Cite

“…• Increased network protein synthesis and • Increased erythrocyte aggregation 37 • Activation of several clotting factors or platelets due to glycoconjugates 38 Recent literature reviews have attributed adverse coagulation effects due to drug-herb interaction in a number of specific herbal remedies, 41,42 The interaction of these preparations with warfarin especially seems to be of significance because of the narrow therapeutic index of warfarin. Of specific concern to the anaesthetist is the interaction between aloe vera and Sevoflurane.…”

Section: The Systemic Effects Of Herbal Medicationmentioning

confidence: 99%

Herbal and alternative medicine: the impact on anesthesia

Dippenaar

2015

Southern African Journal of Anaesthesia and Analgesia

View full text Add to dashboard Cite

The use of herbal and alternative therapies is increasing all over the developed as well as the developing world. As pharmacological data on drug interactions involving herbal therapies becomes available, it is important to be familiar with the challenges that concomitant use of these medications may present within the peri-operative period. This review aims to shed light on the more commonly used herbal drugs, and to discuss drug interactions and complications that may be expected in their use.

show abstract

Possible Interaction Between Sevoflurane and Aloe vera

Abstract: There is a potential herb-drug interaction between Aloe vera and sevoflurane based on the antiplatelet effects of these 2 agents. Herbal medications with antiplatelet potential should be discontinued before anesthesia and surgery.

Cited by 62 publications

References 21 publications

Aloe Vera and Cancer

Aloe Vera and Cancer

Immune Modulation of Aloe vera: Acemannan and Gut Microbiota Modulator

Herbal and alternative medicine: the impact on anesthesia

Contact Info

Product

Resources

About