“…This takes place before the chromatin is tightly condensed in the head of the mature sperm by an ionic crystallization as, for example, in the marine snail Murex brandaris [Amor and Durfort, 1990;Càceres et al, 1994Càceres et al, , 1999Càceres et al, , 2000. Harrison et al [2005] have presented a hypothesis for this transient patterning in the M. brandaris spermatid nucleus, as well as in an octopus and an insect, based on a dynamic mechanism known as spinodal decomposition [Cahn, 1965]. In this process there is a gradual separation between two phases, chromatin and nucleoplasm, during the initial approach of the spermatid Spinodal decomposition occurs uniformly throughout the entire chromatin/nucleoplasm, as seen in glutaraldehyde-fixed spermatids of the marine snail M. brandaris and the octopus Eledone cirrhosa [Harrison et al, 2005].…”