This paper presents a biophysical model of the recognition process of glow patterns (response) of the skin in the area of biologically active zones to external optical activation. The model was developed to increase the efficiency of the process of identifying the causes of differences in glow patterns. The structures of glow patterns are described and their differences are described. A rationale for the use of forced radiation of skin cells in current studies is given (recognition of weak signals of spontaneous radiation is technically difficult). Forced radiation of biological objects appears as a result of excitation of the biological environment by an external action and is much higher than spontaneous radiation. Spontaneous optical radiation of skin cells under certain conditions is one of the characteristic features of the skin. This radiation can be caused by a field form of intercellular interaction, which causes biochemiluminescence in the form of spontaneous weak signals ensuring intercellular communication. The model uses a biotechnical system related to the human physical state, its characteristics, type of meridian and external conditions. We have identified subsystems (biological and technical), the main elements of the system, determined the links between them, necessary and sufficient for drawing conclusions, formulated the main requirements for the system, determined the initial data. The results of the preliminary experimental investigations with the use of the developed model are presented in which some dependence of the luminescence patterns on the meridian type is revealed. It is noted that final conclusions on the causes of skin glow patterns differences in certain points of biologically active zones will be made when more extensive statistical data is collected using the developed model.