Possible Sedative Agents. II. Some Substituted Acetoacetamides

Es wurden einige α‐acylierte Diäthylacetamide dargestellt und der pharmakologischen Vorprüfung zugeführt. Diese ergab, dass von den acht neuen Präparaten drei, die Propionyl‐, Isobutyryl‐ und Hexahydrobenzoyl‐Verbindung, eine analgetische Wirkung auszuüben vermögen. Das wirksamste dieser drei Produkte, die Hexahydrobenzoyl‐Verbindung, ist ungefähr gleich stark analgetisch wirksam wie Pyramidon, aber viermal weniger toxisch.

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Synthese und analgetische Wirkung einiger α‐acylierter Diäthylacetamide

Büchi

Schneeberger

Lieberherr

1953

Helvetica Chimica Acta

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Alkylation and Cyclization of Benzoylacetanilides¹

Searles¹,

Ressler²

1958

J. Am. Chem. Soc.

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The Pharmacist as Nonprescription Drug Therapy Manager: Let's Seize the Opportunity

Covington

2002

Journal of the American Pharmaceutical Association (1996)

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Possible Sedative Agents. II. Some Substituted Acetoacetamides

Cited by 3 publications

References 2 publications

Synthese und analgetische Wirkung einiger α‐acylierter Diäthylacetamide

Synthese und analgetische Wirkung einiger α‐acylierter Diäthylacetamide

Alkylation and Cyclization of Benzoylacetanilides¹

The Pharmacist as Nonprescription Drug Therapy Manager: Let's Seize the Opportunity

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Product

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Possible Sedative Agents. II. Some Substituted Acetoacetamides

Cited by 3 publications

References 2 publications

Synthese und analgetische Wirkung einiger α‐acylierter Diäthylacetamide

Synthese und analgetische Wirkung einiger α‐acylierter Diäthylacetamide

Alkylation and Cyclization of Benzoylacetanilides1

The Pharmacist as Nonprescription Drug Therapy Manager: Let's Seize the Opportunity

Contact Info

Product

Resources

About

Alkylation and Cyclization of Benzoylacetanilides¹