Possible side effects of Intralipid rescue therapy

Smith, Natalie A

doi:10.1111/j.1365-2044.2009.06215.x

Cited by 5 publications

(3 citation statements)

References 9 publications

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“…19 The potential side effects of lipid therapy include erroneously high hemoglobin and platelet counts, and blood gas machine interference. 20 Also, patients with egg or soybean allergies should not receive lipid therapy, as the intralipids are composed of soybean, oil, and egg. Patients with fat metabolism dysfunction such as liver, pancreas, or kidney disease probably should not receive intralipids as it can exacerbate the underlying disease process.…”

Section: Proposed Mechanisms Of Action Of Lipid Emulsionmentioning

confidence: 99%

Lipid Emulsion in Treatment of Local Anesthetic Toxicity

Collins¹,

Neubrander²,

Vorst³

et al. 2015

Journal of PeriAnesthesia Nursing

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Section: Proposed Mechanisms Of Action Of Lipid Emulsionmentioning

confidence: 99%

Lipid Emulsion in Treatment of Local Anesthetic Toxicity

Collins¹,

Neubrander²,

Vorst³

et al. 2015

Journal of PeriAnesthesia Nursing

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“…Lipids can interfere with determination of complete blood cell counts and measurements of serum alanine aminotransferase, albumin, amylase, bilirubin, creatine kinase, creatinine, electrolytes, glucose, lipase, magnesium, phosphate, and total protein. [28][29][30] The interference with laboratory testing can persist up to 24 hours after administration of the lipid. 31 • Pancreatitis: Several possible cases of pancreatitis (temporally associated with the administration of intravenous lipids) have been reported.…”

Section: Adverse Effects Of Intravenous Lipid When Used As An Antidotementioning

confidence: 99%

Intravenous Lipids: Antidotal Therapy for Drug Overdose and Toxic Effects of Local Anesthetics

Bartlett

2014

Critical Care Nurse

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Intravenous lipid emulsion is an accepted therapy for the treatment of severe cardiac toxic effects caused by local anesthetics. Lipid emulsion therapy has also been used successfully to treat cardiac arrest and intractable arrhythmias caused by overdoses of antiepileptic drugs, cardiovascular drugs, and psychotropic medications, but experience with intravenous lipids as antidotal therapy in these clinical situations is limited. However, intravenous lipids are relatively safe, widely available, and easy to administer, and many published case reports document their dramatic effectiveness. Patients who have not responded to standard therapies have been quickly revived by administration of intravenous lipids. Use of lipids most likely will increase, and critical care nurses should be familiar with lipid therapy.

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“…Because of the lipemia, laboratory studies may be diffi cult to analyze transiently or may produce spurious results. 132 It is important to recognize that propofol is not a substitute for ILE, because of myocardial depressant effects and different lipid content. 133…”

Section: Lipid Emulsionmentioning

confidence: 99%