Post-Acute Respiratory Distress Syndrome Pulmonary Fibrosis and Pulmonary Artery Hypertension in Patients Affected by Severe COVID19

Sadigov, Alizamin; Akhundov, S.; Agayeva, A.

doi:10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4456

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Lung Changes In Ards1

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2021

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“…PAH in ARDS did not increase mortality of ARDS, which was 36.6% for both groups [ 21 ]. PAH after recovery from ARDS was also reported in 60% of survivors with SARS-CoV-2 [ 22 ]. Increased circulating endothelin 1 (ET-1) levels and local deposition of hyaluronan/hyaluronic acid (HYA) in the lung parenchyma are indicators for PAH [ 23 ].…”

Section: Lung Changes In Ardsmentioning

confidence: 94%

Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

Frőhlich

2021

Biomedicines

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Acute respiratory distress syndrome (ARDS) is a serious affection of the lung caused by a variety of pathologies. Great interest is currently focused on ARDS induced by viruses (pandemic influenza and corona viruses). The review describes pulmonary changes in ARDS and specific effects of the pandemic viruses in ARDS, and summarizes treatment options. Because the known pathogenic mechanisms cannot explain all aspects of the syndrome, the contribution of pulmonary lymphatics to the pathology is discussed. Organization and function of lymphatics in a healthy lung and in resorption of pulmonary edema are described. A future clinical trial may provide more insight into the role of hyaluronan in ARDS but the development of promising pharmacological treatments is unlikely because drugs play no important role in lymphedema therapy.

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Section: Lung Changes In Ardsmentioning

confidence: 94%

Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

Frőhlich

2021

Biomedicines

View full text Add to dashboard Cite

show abstract

Post-Acute Respiratory Distress Syndrome Pulmonary Fibrosis and Pulmonary Artery Hypertension in Patients Affected by Severe COVID19

Cited by 1 publication

References 0 publications

Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

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