“…Correlation of the patient's history and clinical presentation established the diagnosis of POTASH [10]. In addition to POTASH, other causes of acute hand swelling include allergic contact dermatitis, compartment syndrome, deep venous thrombosis, erythromelalgia, exercise-induced urticaria, infection, irritant contact dermatitis, medications, nocturnal hand swelling, post coronavirus disease 2019 (COVID-19) puffy hands, Raynaud disease and phenomenon, remitting seronegative symmetrical synovitis with pitting edema, and thoracic outlet syndrome [1,2,5,6,8,[10][11][12]. In contrast, chronic hand swelling can result from acromegaly, carpal tunnel syndrome (tumor associated), complex regional pain syndrome type I, leprosy, lymphedema, mixed connective tissue disease, puffy hand syndrome, rheumatoid arthritis, scleroderma, and systemic organ (heart, kidney, and liver) disease [2][3][4]7,9].…”