“…Since the first utilization in 1957 (Neumann, 1957), the use of tissue expansions have become widespread in maxillary and craniofacial surgery (Kobus, 2007), burn scar excision (Hafezi et al, 2009), breast reconstruction following mastectomy (Lohsiriwat et al, 2013), ophthalmology (Hou et al, 2012), management of omphalocele (Clifton et al, 2011), nasal reconstruction (Kheradmand et al, 2011), scalp alopecia (Guzey et al, 2015) and other deformities in plastic reconstructive surgery (Motamed et al, 2008; Laurence et al, 2012; Santiago et al, 2012). Tissue expander generates new tissues, by exploiting the viscoelastic properties of the skin and adjusted histological changes which follows the principle of the controlled mechanical skin overstretch (Argenta, 1984; Pamplona et al, 2014).…”