Post-cholecystectomy Quality of Life: A Prospective Multicenter Cohort Study of Its Associations with Preoperative Functional Status and Patient Demographics

Abstract

The data revealed dramatically improved post-cholecystectomy QOL. However, QOL change was simultaneously associated with preoperative functional status and demographic characteristics.

Long-term outcomes of laparoscopic cholecystectomy: a prospective piecewise linear regression analysis

“…The generalized estimating equations (GEEs) approach was used to interpret score changes for each time interval. For describing longitudinal change, GEEs are advantageous because they can be used even if the number of patient observations or the time intervals between observations vary [3].…”

“…Furthermore, because the health outcome variables cannot continue improving indefinitely, a quadratic time variable was introduced into the equation [3]. If the value of threshold time level is represented by X*, the equation becomes:…”

“…Each SF-36 subscale was converted to a scale of 0 to 100: the higher the score, the better the HRQoL. A translated version of the SF-36 has been validated in Chinese populations [3].…”

“…Studies indicate that LC surgery substantially improves HRQoL [3,4]. Instruments for measuring HRQoL may be disease-specific or generic [5,6].…”

“…Despite their contributions, previous studies of the longterm outcomes for LC have had significant shortcomings [1][2][3][7][8][9]. First, few used longitudinal data with more than two time points.…”