Post‒COVID-19 Condition Treatment and Management Rapid Scoping Review

Abstract


 This rapid living scoping review provides an up-to-date map of the latest published evidence, and identifies research gaps regarding the treatment and management for post–COVID-19 condition.
 Most of the included studies were from a few countries, particularly the US, the UK, and Canada. Also, most of the studies were case reports or series, meaning they included few participants.
 Most of the identified published research on treatments for post‒COVID-19 condition focused on:
 
 vaccines administered 3 months after initial infection
 pharmacological interventions for cardiovascular, neurological, and pulmonary symptoms and diagnoses
 non-pharmacological interventions for pulmonary symptoms.
 
 
 There were fewer studies related to other types of symptoms and organ systems.
 There were notable evidence gaps across all treatments for post–COVID-19 condition, as noted by most of the evidence being from case reports, in which physicians may more often report patients with uncommon symptoms or diagnoses.

Hyperbaric Oxygen Therapy: An Emerging Therapy for Post–COVID-19 Condition

“…Supporting people's recovery from post-COVID-19 condition requires a multidisciplinary approach. 3 With more than 300 trials under way assessing different pharmacological and nonpharmacological interventions to treat post-COVID-19 condition 25 (refer to CADTH's scoping review 26 for a detailed review on interventions), determining the most suitable treatment options will require better understanding of the condition's underlying pathophysiology (or pathophysiologies) and delivering care with a person-centred approach. HBOT could be a part of that treatment journey for some people, but more evidence from randomized trials and registrybased research is likely needed to determine its effectiveness and place in care.…”