Post COVID-19 osteoporosis and avascular necrosis of femoral head: A case report

Joshi, Sachindra Raj; Mahmud, Chowdhury Iqbal; Selimullah, Azm; Sidny, Nabil Zunayed

doi:10.22271/ortho.2021.v7.i4c.2881

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…Regarding the same area, Ardakani et al [14] administered patients with severe infection a 1695.2 mg mean dose of prednisolone and 40 days later they presented with hip ONC. Generally, the most preferred dosage is around 500 and 800 mg of methylprednisolone [29,30], as Jayapalan et al [26] presents a young woman with bilateral hip AVN after a combination of oral and IV methylprednisolone and Daltro et al [35] illustrates 33% osteonecrosis of the femoral head, in patients with severe SARS infection. However, Alkindi et al [18] combined experimental anti-COVID-19 therapies (favipiravir, hydroxychloroquine, tocilizumab) and 200 mg of methylprednisolone and the patient experienced mild signs of hip AVN, which was improved with NSAIDs and PT.…”

Section: Discussionmentioning

confidence: 99%

“…As for the surgical intervention, the option that is favored is core decompression often in combination with BMAC and next the THA. It seems that the first type of treatments was chosen mostly for the younger and more active patients [20,30,31] and when THA is chosen, the direct approach is the preferred one [14]. Only one case reported by Ardakani et al [14] involved infection post-THA due to…”

Section: Discussionmentioning

confidence: 99%

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A Comprehensive Review of COVID-19-Infection- and Steroid-Treatment-Associated Bone Avascular Necrosis: A Multi-Study Analysis

Sakellariou,

Argyropoulou,

Karampinas

et al. 2024

Diagnostics

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Background: The COVID-19 pandemic has presented numerous challenges to the global healthcare system and emerging evidence suggests a potential link between COVID-19 treatment, specifically steroid therapy, and the development of avascular necrosis (AVN) of the hip. This review aims to provide a comprehensive overview of recent studies and case reports investigating the relationship between COVID-19, corticosteroid therapy, and the development of AVN. Understanding the nuances of AVN in the context of COVID-19 is crucial for healthcare professionals to navigate treatment decisions and mitigate potential complications. Materials and Methods: The Preferred Reporting Items for Systematic Reviews and a Meta-Analysis (PRISMA) were used in the systematic review until 1 September 2023. The full texts of the remaining twenty-three (n = 23) articles were independently reviewed by the authors of this review. Conclusions: The association between steroid therapy for COVID-19 and the development of hip AVN is a noteworthy concern even though no relationship is evident between the duration of treatment, cumulative dosage of medication, maximum daily dosage received, and presence of AVN. Further research with larger cohorts and long-term follow up is needed to better understand the causative relationship and optimal management strategies for hip AVN in the context of COVID-19 and steroid therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Comprehensive Review of COVID-19-Infection- and Steroid-Treatment-Associated Bone Avascular Necrosis: A Multi-Study Analysis

Sakellariou,

Argyropoulou,

Karampinas

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

“…In the same area worked Ardakani et al (21) who administered the patients with severe infection with 1695.2 mg mean dose of prednisolone and 40 days later they presented with hip ONC. Generally the most preferred dosage is around 500 and 800 mg methylprednisolone (14) (15), as Jayapalan et al (29) presents a young woman with bilateral hip AVN after a combination of oral and IV methylprednisolone and Daltro et al (32), illustrates a 33% of osteonecrosis of the femoral head, in patients with severe SARS infection. However, Alkindi et al (12) combined experimental anti-COVID-19 therapies (favipiravir, hydroxychloroquine, tocilizumab) and 200 mg methylprednisolone and the patient experienced mild signs of hip AVN, that was improved with NSAIDs and PT.…”

Section: Discussionmentioning

confidence: 99%

A Comprehensive Review of COVID-19 Infection and Steroid-Associated Treatment Bone Avascular Necrosis: A Multi-Study Analysis

Sakellariou,

Argyropoulou,

Karampinas

et al. 2023

Preprint

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Background: The COVID-19 pandemic has presented numerous challenges to global healthcare system and emerging evidence suggests a potential link between COVID-19 treatment, specifically steroid therapy, and the development of avascular necrosis (AVN) of the hip. This review aims to provide a comprehensive overview of recent studies and case reports investigating the relationship between COVID-19, corticosteroid therapy, and the development of AVN. Understanding the nuances of AVN in the context of COVID-19 is crucial for healthcare professionals to navigate treatment decisions and mitigate potential complications. Materials and Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) was used in the systematic review until September 1st, 2023. The full-texts of the remaining twenty-three (n=23) articles were independently reviewed by the authors of this review. Conclusions: The association between steroid therapy for COVID-19 and the development of hip AVN is a noteworthy concern even though, no relationship is evident between the duration of treatment, cumulative dosage of medication, maximum daily dosage received, and the presence of AVN. Further research with larger cohorts and long-term follow-up is needed to better understand the causative relationship and optimal management strategies for hip AVN in the context of COVID-19 and steroid therapy

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Post COVID-19 osteoporosis and avascular necrosis of femoral head: A case report

Cited by 2 publications

References 9 publications

A Comprehensive Review of COVID-19-Infection- and Steroid-Treatment-Associated Bone Avascular Necrosis: A Multi-Study Analysis

A Comprehensive Review of COVID-19-Infection- and Steroid-Treatment-Associated Bone Avascular Necrosis: A Multi-Study Analysis

A Comprehensive Review of COVID-19 Infection and Steroid-Associated Treatment Bone Avascular Necrosis: A Multi-Study Analysis

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