Post-COVID-19 syndrome: nature of symptoms and associated factors

Mahmoud, Nagla; Radwan, Nashwa; Alkattan, Abdullah; Hassanien, Mustafa; Elkajam, Elfadil; Alqahtani, Sara; Haji, Alhan Mohammedamin; Alfaifi, Amal; Alfaleh, Amjad; Alabdulkareem, Khaled

doi:10.1007/s10389-022-01802-3

Cited by 11 publications

(4 citation statements)

References 37 publications

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“…As a result, we found that some patients with decompensated cirrhosis also experienced the symptoms of “post-COVID-19 syndrome,” such as cough, fatigue, wheezing, and change or even loss of taste. [ 23 , 24 ] As described by these patients, these symptoms persisted after COVID-19 illness, and in this study, were categorized as the “post-COVID-specific symptom cluster.” The findings of our study, along with those of others [ 25 ] have suggested that these syndromes impact patients’ quality of life to varying degrees.…”

Section: Discussionmentioning

confidence: 79%

A new theory to promote self-management of symptom clusters and healthcare quality in patients with decompensated cirrhosis

Liu,

Luo,

Zhang

et al. 2023

Medicine

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Patients with decompensated cirrhosis, a symptomatic phase of cirrhosis, commonly experience multiple symptoms concurrently, referred to as symptom clusters. Effective self-management of symptoms is known to improve outcomes in various chronic diseases. However, a theory for self-management of symptom clusters in decompensated cirrhosis is lacking. In this study, we applied grounded theory research methodology to construct a new theory of self-management of symptom clusters in these patients. This qualitative study prospectively enrolled 20 patients with decompensated cirrhosis within 1 week after hospital admission. Data related to patients’ experiences, needs, perspectives, and abilities related to their symptoms were collected via a semi-structured, in-depth interview and analyzed with Nvivo version 20 software. Grounded theory methodology with 3 coding steps (open, axial, and selective coding) was applied to generate a theory of self-management of symptom clusters. From the step-by-step coding process, 2 core categories or major themes were identified: patients’ experiences with symptoms and coping with symptoms. The first major theme included symptom clustering, multidimensionality, recurrence, and specificity, while the second consisted of endogenous motivation, endogenous resistance, and external support needs. A new theory of self-management of symptom clusters was then constructed and delineated to enhance self-management among patients with decompensated cirrhosis. Using patient experience data, we developed a new theory of self-management of symptom clusters in patients with decompensated cirrhosis. Use of this theory has the potential to promote patient self-management and guide healthcare providers in planning optimal treatments and implementing timely interventions, ultimately improving in patient outcomes.

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Section: Discussionmentioning

confidence: 79%

A new theory to promote self-management of symptom clusters and healthcare quality in patients with decompensated cirrhosis

Liu,

Luo,

Zhang

et al. 2023

Medicine

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“…Coughing is the most common symptom of COVID-19 sequelae and is present in approximately 23% to 57% of COVID-19 survivors in all countries, and is highly prevalent in both mild and severe cases [ 173 , 174 ]. Cough can persist for months, with a prevalence of up to 2.5% even after one year of recovery [ 175 ], making it a major source of distress for patients.…”

Section: Therapeutic Potential Of Naringin and Naringenin In Long Covidmentioning

confidence: 99%

Potential Beneficial Effects of Naringin and Naringenin on Long COVID—A Review of the Literature

Liu,

Zhong,

et al. 2024

Microorganisms

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Coronavirus disease 2019 (COVID-19) caused a severe epidemic due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Recent studies have found that patients do not completely recover from acute infections, but instead, suffer from a variety of post-acute sequelae of SARS-CoV-2 infection, known as long COVID. The effects of long COVID can be far-reaching, with a duration of up to six months and a range of symptoms such as cognitive dysfunction, immune dysregulation, microbiota dysbiosis, myalgic encephalomyelitis/chronic fatigue syndrome, myocarditis, pulmonary fibrosis, cough, diabetes, pain, reproductive dysfunction, and thrombus formation. However, recent studies have shown that naringenin and naringin have palliative effects on various COVID-19 sequelae. Flavonoids such as naringin and naringenin, commonly found in fruits and vegetables, have various positive effects, including reducing inflammation, preventing viral infections, and providing antioxidants. This article discusses the molecular mechanisms and clinical effects of naringin and naringenin on treating the above diseases. It proposes them as potential drugs for the treatment of long COVID, and it can be inferred that naringin and naringenin exhibit potential as extended long COVID medications, in the future likely serving as nutraceuticals or clinical supplements for the comprehensive alleviation of the various manifestations of COVID-19 complications.

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“…The pathogenesis of post-COVID syndrome involves multiple mechanisms that result in various clinical manifestations. 26 The post-COVID-19 patients were given 10 minutes of inhalation of essential oils containing a mixture of Thymus vulgaris, Citrus sinensis, Eugenia caryophyllus, and Boswellia carterii (essential oils) twice per day for 14 days, which resulted in a significant decrease in fatigue in the Intervention Group. Nevertheless, one participant in the Intervention Group reported experiencing headaches and withdrew on day-13.…”

Section: Efficacymentioning

confidence: 99%

Efficacy and Safety of Add-On Plant-Based Drugs for COVID-19 Patients: A Review of the Randomized Control Trials

Diantini¹,

Febriyanti²,

Levita³

2023

IDR

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COVID-19 caused by the infection of SARS-CoV-2 is still a global concern. WHO reported that from 13 March to 9 April 2023, there were 3 million new cases and approximately 23,000 deaths, mostly occurring in the South-East Asia and Eastern Mediterranean regions, which is predicted due to the new Omicron variant, Arcturus XBB.1.16. Many studies have reported the potency of medicinal plants in enhancing the function of the immune system to combat virus infection. The literature review aimed to describe the efficacy and safety of add-on plant-based drugs for COVID-19 patients. The articles were explored on the PubMed and Cochrane Library databases, and published during 2020-2023. Twenty-two varieties of plants were used as add-on therapy for COVID-19 patients. These plants were

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Post-COVID-19 syndrome: nature of symptoms and associated factors

Cited by 11 publications

References 37 publications

A new theory to promote self-management of symptom clusters and healthcare quality in patients with decompensated cirrhosis

A new theory to promote self-management of symptom clusters and healthcare quality in patients with decompensated cirrhosis

Potential Beneficial Effects of Naringin and Naringenin on Long COVID—A Review of the Literature

Efficacy and Safety of Add-On Plant-Based Drugs for COVID-19 Patients: A Review of the Randomized Control Trials

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