Post-COVID Multisystem Inflammatory Syndrome-Adult Leading to Cardiomyopathy and Autoimmune Thyroiditis: A Case Report

Abstract

The Coronavirus disease pandemic is an evolving disease with myriad presentations and sequelae. Multisystem inflammatory syndrome in adults (MIS-A) can affect various organ systems, including cardiovascular, gastrointestinal, and neurologic systems, with fever and abnormally increased inflammatory markers without significant respiratory affection. This is a well-known complication in children (MIS-C). Validated clinical criteria are used to diagnose this condition. Long-term sequelae of MIS-A are unclear and underreported. Here, we describe a case of Post-COVID-19 MIS-A who presented with cardiac dysfunction, hepatitis, and acute kidney injury and recovered well with steroids. He was left with persistent cardiomyopathy and thyroiditis with hypothyroidism which to date has not fully recovered. This case emphasizes that the sequelae of COVID-19 and its pathophysiology are not fully understood, and more research is needed to predict and prevent the same.

Viral Pneumonia: From Influenza to COVID-19

“…139 Interestingly, a case of post-COVID-19 MIS-A who presented with cardiac dysfunction, hepatitis, and acute kidney injury that recovered well with steroids therapy was described recently, which emphasizes that the sequelae of COVID-19 and its pathophysiology are not fully understood, and we need more research. 140 Recently, a large study was published that evaluated viral RNA load and host responses in critically ill patients with COVID-19. In the study, 836 unvaccinated patients with severe COVID-19 were included.…”