Historical masonry structures with aesthetic aspects play an important role in cultural heritage. However, such structures are vulnerable to seismic effects. Therefore, periodic maintenance and structural evaluations are required for these structures. In this study, a historical masonry building called the Pertev Pasha Mansion, located in Trabzon, Turkey, was selected for the evaluation. The building was demolished in the last few years and has been planned to be rebuilt in its original form. In the study, the finite element model of the building was created based on reconstruction drawings. Modal analysis was performed to obtain the frequencies and mode shapes of the building. Finally, seismic analyses were conducted based on the February 6 Kahramanmaraş earthquakes for two different acceleration records that were collected from different stations, one near the epicenter (Pazarcık station) of the earthquake and the other near the building (Ortahisar station). From the results of the modal analysis, the frequency and mode shapes of the structure were obtained. The displacement and stress results were obtained from the seismic analysis and presented with contour diagrams. At the end of the study, a general evaluation considering the novel Turkish guidelines for historic structures was conducted. According to the results of the seismic analysis performed using the Pazarcık station data, the drift ratio values of the structure exceeded 0.7%, which corresponds to the Collapse Prevention (CP) performance level. However, according to the seismic analysis results obtained using Ortahisar station data, the maximum drift ratio of the structure was 0.001%, corresponding to the Limited Damage (LD) performance level. Consequently, if the building had been built close to the center of the earthquake, it was likely to collapse, but it was estimated that it would have received limited damage because its current location was far from the center of the earthquake.